9HJZ
Crystal structure of human geranylgeranyl diphosphate synthase mutant Y246D
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Geranylgeranyl pyrophosphate synthase | polymer | 307 | 35388.2 | 2 | UniProt (O95749) Pfam (PF00348) | Homo sapiens (human) | GGPP synthase,GGPPSase,(2E,6E)-farnesyl diphosphate synthase,Dimethylallyltranstransferase,Farnesyl diphosphate synthase,Farnesyltranstransferase,Geranylgeranyl diphosphate synthase,Geranyltranstransferase |
| 2 | C (A) | CITRIC ACID | non-polymer | 192.1 | 1 | Chemie (CIT) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 34 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 300 (UniProt: O95749)
| PDB | External Database | Details |
|---|---|---|
| Gly -6 | - | expression tag |
| Ser -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Gln 109 | Pro 109 | variant |
| Asp 246 | Tyr 246 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 70776.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 192.1 | |
| All* | Total formula weight | 70968.5 |
