9HJQ

ROCK2 bound with TDI01

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Rho-associated protein kinase 2	polymer	401	45929.2	2	UniProt (O75116)	Homo sapiens (human)	Rho kinase 2,Rho-associated,coiled-coil-containing protein kinase 2,coiled-coil-containing protein kinase II,ROCK-II,p164 ROCK-2
2	C, D (A, B)	[3,3-bis(fluoranyl)azetidin-1-yl]-[1-methyl-6-[4-[[4-(1~{H}-pyrazol-4-yl)phenyl]amino]pyrimidin-2-yl]indol-2-yl]methanone	non-polymer		485.5	2	Chemie (A1IVI)

Sequence modifications

A, B: 18 - 417 (UniProt: O75116)

PDB	External Database	Details
Met 17	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	91858.5
Non-Polymers*	Number of molecules	2
	Total formula weight	971.0
All*	Total formula weight	92829.4

*Water molecules are not included.