9HIA
K115 acetylated human muscle pyruvate kinase, isoform M2 (PKM2), in complex with FBP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Pyruvate kinase PKM | polymer | 537 | 58886.8 | 4 | UniProt (P14618) Pfam (PF00224) Pfam (PF02887) | Homo sapiens (human) | Cytosolic thyroid hormone-binding protein,CTHBP,Opa-interacting protein 3,OIP-3,Pyruvate kinase 2/3,Pyruvate kinase muscle isozyme,Threonine-protein kinase PKM2,Thyroid hormone-binding protein 1,THBP1,Tumor M2-PK,Tyrosine-protein kinase PKM2,p58 |
| 2 | E, K, O, U (A, B, C, D) | 1,6-di-O-phosphono-beta-D-fructofuranose | non-polymer | 340.1 | 4 | Chemie (FBP) | |||
| 3 | F, G, H, I, L... (A, B, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 7 | Chemie (EDO) | |||
| 4 | J, N, Q, W (A, B, C, D) | SUCCINIC ACID | non-polymer | 118.1 | 4 | Chemie (SIN) | |||
| 5 | P, R (C) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 6 | S, T (C) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 7 | AA, X, Y, Z (D, A, B, C) | water | water | 18.0 | 1418 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 531 (UniProt: P14618)
| PDB | External Database | Details |
|---|---|---|
| His 532 | - | expression tag |
| His 533 | - | expression tag |
| His 534 | - | expression tag |
| His 535 | - | expression tag |
| His 536 | - | expression tag |
| His 537 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 235547.1 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 2529.7 | |
| All* | Total formula weight | 238076.8 |
