9HH6
Crystal Structure of Nsp15 Endoribonuclease from SARS CoV-2 in Complex with TAS-103
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ORF1ab polyprotein | polymer | 347 | 38994.4 | 1 | UniProt (A0A8B6RHF8) Pfam (PF19219) Pfam (PF19216) Pfam (PF19215) UniProt (by SIFTS) (A0A8B6RWT5) | Severe acute respiratory syndrome coronavirus 2 | |
| 2 | B (B) | ORF1ab polyprotein | polymer | 345 | 38752.1 | 1 | UniProt (A0A8B1JY75) Pfam (PF19219) Pfam (PF19216) Pfam (PF19215) UniProt (by SIFTS) (A0A8B6RWT5) | Severe acute respiratory syndrome coronavirus 2 | |
| 3 | C, I (A, B) | 6-[2-(dimethylamino)ethylamino]-3-oxidanyl-indeno[2,1-c]quinolin-7-one | non-polymer | 333.4 | 2 | Chemie (A1IUV) | |||
| 4 | D, J (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 5 | E, F, G, H, K... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 6 | M, N (A, B) | water | water | 18.0 | 367 | Chemie (HOH) |
Sequence modifications
A: 2 - 346 (UniProt: A0A8B6RHF8)
B: 2 - 344 (UniProt: A0A8B1JY75)
| PDB | External Database | Details |
|---|---|---|
| His 0 | - | expression tag |
| Met 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| His 0 | - | expression tag |
| Met 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 77746.5 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1229.1 | |
| All* | Total formula weight | 78975.6 |
