9HG0

Crystal structure of M. smegmatis GMP reductase with XMP* intermidiate in complex with NADP+ and IMP.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	GMP reductase	polymer	496	51782.4	8	UniProt (A0QYE8) Pfam (PF00478) Pfam (PF00571)	Mycolicibacterium smegmatis	Guanosine 5'-monophosphate reductase,GMPR
2	AA, CA, EA, FA, I... (G, H, A, B, C...)	INOSINIC ACID	non-polymer		348.2	16	Chemie (IMP)
3	BA, DA, J, M, P... (G, A, B, C, D...)	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	8	Chemie (NAP)
4	GA, HA, IA, JA, KA... (A, B, C, D, E...)	water	water		18.0	741	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 1 - 479 (UniProt: A0QYE8)

PDB	External Database	Details
Val 2	-	insertion
Thr 480	-	expression tag
Ala 481	-	expression tag
Ala 482	-	expression tag
Ala 483	-	expression tag
Lys 484	-	expression tag
Glu 485	-	expression tag
Asp 486	-	expression tag
Leu 487	-	expression tag
Glu 488	-	expression tag
His 489	-	expression tag
His 490	-	expression tag
His 491	-	expression tag
His 492	-	expression tag
His 493	-	expression tag
His 494	-	expression tag
His 495	-	expression tag
His 496	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	414259.5
Non-Polymers*	Number of molecules	24
	Total formula weight	11518.5
All*	Total formula weight	425778.0

*Water molecules are not included.