9HF3

CryoEM structure of mouse Panx1-Y308E

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Pannexin-1	polymer	444	50219.1	7	UniProt (Q9JIP4) Pfam (PF00876)	Mus musculus (house mouse)
2	H, I, J, K, L... (A, B, C, D, E...)	CHOLESTEROL HEMISUCCINATE	non-polymer		486.7	14	Chemie (Y01)
3	AA, BA, V, W, X... (F, G, A, B, C...)	water	water		18.0	21	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G: 1 - 426 (UniProt: Q9JIP4)

PDB	External Database	Details
Glu 308	Tyr 308	engineered mutation
Gly 427	-	expression tag
Ser 428	-	expression tag
Ala 429	-	expression tag
Ala 430	-	expression tag
Ala 431	-	expression tag
Glu 432	-	expression tag
Asn 433	-	expression tag
Leu 434	-	expression tag
Tyr 435	-	expression tag
Phe 436	-	expression tag
Gln 437	-	expression tag
Gly 438	-	expression tag
His 439	-	expression tag
His 440	-	expression tag
His 441	-	expression tag
His 442	-	expression tag
His 443	-	expression tag
His 444	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	7
	Total formula weight	351533.8
Non-Polymers*	Number of molecules	14
	Total formula weight	6814.2
All*	Total formula weight	358348.0

*Water molecules are not included.