9HDM

Crystal structure of Pyrimidine Nucleoside 2'-Hydroxylase (PDN2'H) from Neurospora crassa in complex with thymidine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Clavaminate synthase-like protein	polymer	390	42508.7	2	UniProt (Q7SHQ5)	Neurospora crassa
2	C, F (A, B)	MANGANESE (II) ION	non-polymer		54.9	2	Chemie (MN)
3	D, H (A, B)	THYMIDINE	non-polymer		242.2	2	Chemie (THM)
4	E (A)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
5	G (B)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
6	I (B)	(R,R)-2,3-BUTANEDIOL	non-polymer		90.1	1	Chemie (BU3)
7	J, K (A, B)	water	water		18.0	654	Chemie (HOH)

Sequence modifications

A, B: 1 - 370 (UniProt: Q7SHQ5)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	85017.3
Non-Polymers*	Number of molecules	7
	Total formula weight	782.0
All*	Total formula weight	85799.3

*Water molecules are not included.