9HDF

Glucocorticoid Receptor Ligand Binding Domain in complex with dexamethasone

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, D, F, G... (A, C, D, F, G...)	Ancestral Glucocorticoid Receptor2 ligand binding domain	polymer	248	28649.4	10		Homo sapiens
2	B, E, J, K, N... (B, E, J, K, N...)	Ancestral Glucocorticoid Receptor2 ligand binding domain	polymer	248	28665.4	6		Homo sapiens
3	AA, BA, CA, DA, EA... (a, b, c, d, e...)	Nuclear receptor subfamily 0 group B member 2	polymer	15	1562.8	16	UniProt (Q15466)	Homo sapiens	Orphan nuclear receptor SHP,Small heterodimer partner
4	AD, EB, EC, GA, GD... (M, D, J, A, N...)	DEXAMETHASONE	non-polymer		392.5	16	Chemie (DEX)
5	BD, DB, HA, JB, LD... (M, D, A, E, O...)	CACODYLATE ION	non-polymer		137.0	8	Chemie (CAC)
6	AC, FC, GB, IA, PA... (I, J, D, A, B...)	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID	non-polymer		238.3	7	Chemie (EPE)
7	BC, GC, HC, HD, IC... (I, J, N, A, E...)	GLYCEROL	non-polymer		92.1	20	Chemie (GOL)
8	AB, BB, DC, LA, TA (C, J, A, B)	SULFATE ION	non-polymer		96.1	5	Chemie (SO4)
9	CB, FD, HB, JD, LC... (C, M, D, N, J...)	CHLORIDE ION	non-polymer		35.5	11	Chemie (CL)
10	FB, OA, SC, WB (D, B, L, H)	TETRAETHYLENE GLYCOL	non-polymer		194.2	4	Chemie (PG4)
11	CC, ED, ID, JC, KC... (I, M, N, J, E...)	IMIDAZOLE	non-polymer		69.1	15	Chemie (IMD)
12	DD, MC, QB, ZB (M, K, F, I)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	4	Chemie (PEG)
13	CD (M)	TRIETHYLENE GLYCOL	non-polymer		150.2	1	Chemie (PGE)
14	AE, TD, UD, VD, WD... (i, D, I, J, K...)	water	water		18.0	13	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	32
	Total formula weight	483491.1
Non-Polymers*	Number of molecules	91
	Total formula weight	14143.4
All*	Total formula weight	497634.5

*Water molecules are not included.