9HCF
Mouse mitoribosome large subunit assembly intermediate bound to NSUN4, METRF4, GTPBP7, GTPBP10 and the MALSU-L0R8F8-mtACP complex with uL16m, State B2 (SAMC knock-out)
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 16S rRNA (1432-MER) | polymer | 1584 | 508610.0 | 1 | GenBank (10336604) | Mus musculus (house mouse) | |
| 2 | B (B) | RNA (63-MER) | polymer | 68 | 21862.1 | 1 | GenBank (10336604) | Mus musculus (house mouse) | |
| 3 | C (D) | Large ribosomal subunit protein uL2m | polymer | 246 | 27168.5 | 1 | UniProt (Q9D773) Pfam (PF00181) Pfam (PF03947) | Mus musculus (house mouse) | 39S ribosomal protein L2,mitochondrial,L2mt,MRP-L2 |
| 4 | D (E) | Large ribosomal subunit protein uL3m | polymer | 348 | 39170.9 | 1 | UniProt (Q99N95) Pfam (PF00297) | Mus musculus (house mouse) | 39S ribosomal protein L3,mitochondrial,L3mt,MRP-L3 |
| 5 | E (F) | Large ribosomal subunit protein uL4m | polymer | 294 | 33120.1 | 1 | UniProt (Q9DCU6) Pfam (PF00573) | Mus musculus (house mouse) | 39S ribosomal protein L4,mitochondrial,L4mt,MRP-L4 |
| 6 | F (H) | Large ribosomal subunit protein bL9m | polymer | 265 | 30298.1 | 1 | UniProt (Q99N94) Pfam (PF01281) Pfam (PF22078) | Mus musculus (house mouse) | 39S ribosomal protein L9,mitochondrial,L9mt,MRP-L9 |
| 7 | G (I) | Large ribosomal subunit protein uL10m | polymer | 262 | 29438.6 | 1 | UniProt (Q3TBW2) | Mus musculus (house mouse) | 39S ribosomal protein L10,mitochondrial,L10mt,MRP-L10 |
| 8 | H (J) | Large ribosomal subunit protein uL11m | polymer | 192 | 20714.2 | 1 | UniProt (Q9CQF0) Pfam (PF03946) Pfam (PF00298) | Mus musculus (house mouse) | 39S ribosomal protein L11,mitochondrial,L11mt,MRP-L11 |
| 9 | I (K) | Large ribosomal subunit protein uL13m | polymer | 178 | 20707.9 | 1 | UniProt (Q9D1P0) Pfam (PF00572) | Mus musculus (house mouse) | 39S ribosomal protein L13,mitochondrial,L13mt,MRP-L13 |
| 10 | J (L) | Large ribosomal subunit protein uL14m | polymer | 145 | 15900.5 | 1 | UniProt (Q9D1I6) Pfam (PF00238) | Mus musculus (house mouse) | 39S ribosomal protein L14,mitochondrial,L14mt,MRP-L14 |
| 11 | K (M) | Large ribosomal subunit protein uL15m | polymer | 295 | 33595.9 | 1 | UniProt (Q9CPR5) Pfam (PF00828) | Mus musculus (house mouse) | 39S ribosomal protein L15,mitochondrial,L15mt,MRP-L15 |
| 12 | L (N) | Large ribosomal subunit protein uL16m | polymer | 251 | 28850.8 | 1 | UniProt (Q99N93) Pfam (PF00252) | Mus musculus (house mouse) | 39S ribosomal protein L16,mitochondrial,L16mt,MRP-L16 |
| 13 | M (O) | Large ribosomal subunit protein bL17m | polymer | 176 | 20282.4 | 1 | UniProt (Q9D8P4) Pfam (PF01196) | Mus musculus (house mouse) | 39S ribosomal protein L17,mitochondrial,L17mt,MRP-L17 |
| 14 | N (P) | Large ribosomal subunit protein uL18m | polymer | 180 | 20707.8 | 1 | UniProt (Q9CQL5) Pfam (PF00861) | Mus musculus (house mouse) | 39S ribosomal protein L18,mitochondrial,L18mt,MRP-L18 |
| 15 | O (Q) | Large ribosomal subunit protein bL19m | polymer | 292 | 33629.0 | 1 | UniProt (Q9D338) Pfam (PF01245) | Mus musculus (house mouse) | 39S ribosomal protein L19,mitochondrial,L19mt,MRP-L19 |
| 16 | P (R) | Large ribosomal subunit protein bL20m | polymer | 149 | 17631.8 | 1 | UniProt (Q9CQL4) Pfam (PF00453) | Mus musculus (house mouse) | 39S ribosomal protein L20,mitochondrial,L20mt,MRP-L20 |
| 17 | Q (S) | Large ribosomal subunit protein bL21m | polymer | 209 | 23401.3 | 1 | UniProt (Q9D1N9) Pfam (PF00829) | Mus musculus (house mouse) | 39S ribosomal protein L21,mitochondrial,L21mt,MRP-L21 |
| 18 | R (T) | Large ribosomal subunit protein uL22m | polymer | 206 | 23847.9 | 1 | UniProt (Q8BU88) Pfam (PF00237) | Mus musculus (house mouse) | 39S ribosomal protein L22,mitochondrial,L22mt,MRP-L22 |
| 19 | S (U) | Large ribosomal subunit protein uL23m | polymer | 146 | 17145.6 | 1 | UniProt (O35972) Pfam (PF00276) | Mus musculus (house mouse) | 39S ribosomal protein L23,mitochondrial,L23mt,MRP-L23,L23 mitochondrial-related protein |
| 20 | T (V) | Large ribosomal subunit protein uL24m | polymer | 216 | 24986.6 | 1 | UniProt (Q9CQ06) Pfam (PF00467) Pfam (PF17136) | Mus musculus (house mouse) | 39S ribosomal protein L24,mitochondrial,L24mt,MRP-L24 |
| 21 | U (W) | Large ribosomal subunit protein bL27m | polymer | 148 | 15973.6 | 1 | UniProt (Q99N92) Pfam (PF01016) | Mus musculus (house mouse) | 39S ribosomal protein L27,mitochondrial,L27mt,MRP-L27 |
| 22 | V (X) | Large ribosomal subunit protein bL28m,Large ribosomal subunit protein bL32m | polymer | 294 | 34560.8 | 1 | UniProt (Q9D1B9) UniProt (Q9DCI9) Pfam (PF00830) | Mus musculus (house mouse) | 39S ribosomal protein L28,mitochondrial,L28mt,MRP-L28,39S ribosomal protein L32,mitochondrial,L32mt,MRP-L32,Heart-expressed gene 1 protein |
| 23 | W (Y) | Large ribosomal subunit protein uL29m | polymer | 252 | 29786.7 | 1 | UniProt (Q8K2Y7) Pfam (PF06984) | Mus musculus (house mouse) | 39S ribosomal protein L47,mitochondrial,L47mt,MRP-L47 |
| 24 | X (Z) | Large ribosomal subunit protein uL30m | polymer | 160 | 18380.6 | 1 | UniProt (Q9D7N6) Pfam (PF00327) | Mus musculus (house mouse) | 39S ribosomal protein L30,mitochondrial,L30mt,MRP-L30 |
| 25 | Y (x) | 5-cytosine rRNA methyltransferase NSUN4 | polymer | 381 | 42904.3 | 1 | UniProt (Q9CZ57) Pfam (PF01189) | Mus musculus (house mouse) | 5-cytosine tRNA methyltransferase NSUN4,NOL1/NOP2/Sun domain family member 4,Sperm head and tail associated protein |
| 26 | Z (1) | Large ribosomal subunit protein bL33m | polymer | 65 | 7431.9 | 1 | UniProt (Q9CQP0) Pfam (PF00471) | Mus musculus (house mouse) | 39S ribosomal protein L33,mitochondrial,L33mt,MRP-L33 |
| 27 | AA (2) | Large ribosomal subunit protein bL34m | polymer | 92 | 10552.5 | 1 | UniProt (Q99N91) Pfam (PF00468) | Mus musculus (house mouse) | 39S ribosomal protein L34,mitochondrial,L34mt,MRP-L34 |
| 28 | BA (3) | Large ribosomal subunit protein bL35m | polymer | 188 | 21546.4 | 1 | UniProt (Q9CQL6) Pfam (PF01632) | Mus musculus (house mouse) | 39S ribosomal protein L35,mitochondrial,L35mt,MRP-L35 |
| 29 | CA (4) | Large ribosomal subunit protein bL36m | polymer | 101 | 11439.0 | 1 | UniProt (Q99N90) Pfam (PF00444) | Mus musculus (house mouse) | 39S ribosomal protein L36,mitochondrial,L36mt,MRP-L36 |
| 30 | DA (6) | Large ribosomal subunit protein mL38 | polymer | 380 | 45099.9 | 1 | UniProt (Q8K2M0) Pfam (PF01161) | Mus musculus (house mouse) | 39S ribosomal protein L38,mitochondrial,L38mt,MRP-L38 |
| 31 | EA (7) | Large ribosomal subunit protein mL39 | polymer | 336 | 38603.3 | 1 | UniProt (Q9JKF7) | Mus musculus (house mouse) | 39S ribosomal protein L39,mitochondrial,L39mt,MRP-L39 |
| 32 | FA (b) | Large ribosomal subunit protein mL43 | polymer | 159 | 17905.3 | 1 | UniProt (Q5RL20) Pfam (PF05047) | Mus musculus (house mouse) | |
| 33 | GA (f) | Large ribosomal subunit protein mL48 | polymer | 211 | 23989.7 | 1 | UniProt (Q8JZS9) Pfam (PF00338) | Mus musculus (house mouse) | 39S ribosomal protein L48,mitochondrial,L48mt,MRP-L48 |
| 34 | HA (h) | Large ribosomal subunit protein mL50 | polymer | 159 | 18241.0 | 1 | UniProt (Q8VDT9) Pfam (PF10501) | Mus musculus (house mouse) | 39S ribosomal protein L50,mitochondrial,L50mt,MRP-L50 |
| 35 | IA (i) | Large ribosomal subunit protein mL51 | polymer | 128 | 15132.8 | 1 | UniProt (Q9CPY1) Pfam (PF10244) | Mus musculus (house mouse) | 39S ribosomal protein L51,mitochondrial,L51mt,MRP-L51,bMRP-64,bMRP64 |
| 36 | JA (j) | Large ribosomal subunit protein mL52 | polymer | 121 | 13681.9 | 1 | UniProt (Q9D0Y8) Pfam (PF18699) | Mus musculus (house mouse) | 39S ribosomal protein L52,mitochondrial,L52mt,MRP-L52 |
| 37 | KA (o) | Large ribosomal subunit protein mL63 | polymer | 102 | 11974.8 | 1 | UniProt (Q9CQF8) Pfam (PF14978) | Mus musculus (house mouse) | Mitochondrial ribosomal protein 63,Mitochondrial ribosomal protein L57,Ribosomal protein 63,mitochondrial,mMRP63 |
| 38 | LA (q) | Large ribosomal subunit protein mL64 | polymer | 222 | 25865.5 | 1 | UniProt (Q9CR59) Pfam (PF10147) | Mus musculus (house mouse) | 39S ribosomal protein L59,mitochondrial,MRP-L59,Growth arrest and DNA damage-inducible proteins-interacting protein 1 |
| 39 | MA (r) | Large ribosomal subunit protein mL66 | polymer | 196 | 22363.5 | 1 | UniProt (Q99N85) Pfam (PF01084) | Mus musculus (house mouse) | 28S ribosomal protein S18-3,mitochondrial,MRP-S18-3,28S ribosomal protein S18a,MRP-S18-a,Mrps18a,S18mt-a |
| 40 | NA (s) | Large ribosomal subunit protein mL65 | polymer | 442 | 50005.2 | 1 | UniProt (Q9D0G0) Pfam (PF07147) | Mus musculus (house mouse) | 28S ribosomal protein S30,mitochondrial,MRP-S30,S30mt |
| 41 | OA (u) | Mitochondrial assembly of ribosomal large subunit protein 1 | polymer | 228 | 26055.1 | 1 | UniProt (Q9CWV0) Pfam (PF02410) | Mus musculus (house mouse) | |
| 42 | PA (v) | Predicted gene, 55359 | polymer | 70 | 8444.8 | 1 | UniProt (A0A2I3BQS8) Pfam (PF05347) | Mus musculus (house mouse) | |
| 43 | QA (5) | Large ribosomal subunit protein mL37 | polymer | 423 | 48407.7 | 1 | UniProt (Q921S7) Pfam (PF07147) | Mus musculus (house mouse) | 39S ribosomal protein L37,mitochondrial,L37mt,MRP-L37 |
| 44 | RA (8) | Large ribosomal subunit protein mL40 | polymer | 206 | 24347.1 | 1 | UniProt (Q9Z2Q5) Pfam (PF09812) | Mus musculus (house mouse) | 39S ribosomal protein L40,mitochondrial,L40mt,MRP-L40,Nuclear localization signal-containing protein deleted in velocardiofacial syndrome homolog |
| 45 | SA (9) | Large ribosomal subunit protein mL41 | polymer | 135 | 15284.6 | 1 | UniProt (Q9CQN7) Pfam (PF09809) | Mus musculus (house mouse) | 39S ribosomal protein L41,mitochondrial,L41mt,MRP-L41 |
| 46 | TA (a) | Large ribosomal subunit protein mL42 | polymer | 142 | 16521.8 | 1 | UniProt (Q9CPV3) Pfam (PF10210) | Mus musculus (house mouse) | 28S ribosomal protein S32,mitochondrial,MRP-S32,S32mt,39S ribosomal protein L31,L31mt,MRP-L31,39S ribosomal protein L42,L42mt,MRP-L42 |
| 47 | UA (m) | Large ribosomal subunit protein mL55 | polymer | 127 | 15152.6 | 1 | UniProt (Q9CZ83) Pfam (PF09776) | Mus musculus (house mouse) | 39S ribosomal protein L55,mitochondrial,L55mt,MRP-L55 |
| 48 | VA (z) | Mitochondrial ribosome-associated GTPase 1 | polymer | 326 | 36732.0 | 1 | UniProt (Q8R2R6) Pfam (PF01926) | Mus musculus (house mouse) | GTP-binding protein 7,Mitochondrial GTPase 1 |
| 49 | WA (l) | Large ribosomal subunit protein mL54 | polymer | 135 | 15450.9 | 1 | UniProt (Q9CPW3) Pfam (PF08561) | Mus musculus (house mouse) | 39S ribosomal protein L54,mitochondrial,L54mt,MRP-L54 |
| 50 | XA (y) | Transcription termination factor 4, mitochondrial | polymer | 346 | 40306.2 | 1 | UniProt (Q8BVN4) Pfam (PF02536) | Mus musculus (house mouse) | Mitochondrial transcription termination factor 4,mTERF domain-containing protein 2 |
| 51 | YA (w) | Acyl carrier protein, mitochondrial | polymer | 156 | 17390.3 | 1 | UniProt (Q9CR21) Pfam (PF00550) | Mus musculus (house mouse) | ACP,CI-SDAP,NADH-ubiquinone oxidoreductase 9.6 kDa subunit |
| 52 | ZA (c) | Large ribosomal subunit protein mL44 | polymer | 308 | 34912.0 | 1 | UniProt (Q9CY73) Pfam (PF22935) Pfam (PF22892) | Mus musculus (house mouse) | 39S ribosomal protein L44,mitochondrial,L44mt,MRP-L44 |
| 53 | AB (g) | Large ribosomal subunit protein mL49 | polymer | 166 | 19161.0 | 1 | UniProt (Q9CQ40) Pfam (PF05046) | Mus musculus (house mouse) | 39S ribosomal protein L49,mitochondrial,L49mt,MRP-L49 |
| 54 | BB (k) | Large ribosomal subunit protein mL53 | polymer | 118 | 12756.6 | 1 | UniProt (Q9D1H8) Pfam (PF10780) | Mus musculus (house mouse) | 39S ribosomal protein L53,mitochondrial,L53mt,MRP-L53 |
| 55 | CB (0) | Large ribosomal subunit protein bL32m | polymer | 187 | 21766.2 | 1 | UniProt (Q9DCI9) Pfam (PF01783) | Mus musculus (house mouse) | 39S ribosomal protein L32,mitochondrial,L32mt,MRP-L32,Heart-expressed gene 1 protein |
| 56 | DB (d) | Large ribosomal subunit protein mL45 | polymer | 306 | 35463.9 | 1 | UniProt (Q9D0Q7) Pfam (PF04280) | Mus musculus (house mouse) | 39S ribosomal protein L45,mitochondrial,L45mt,MRP-L45 |
| 57 | EB (e) | Large ribosomal subunit protein mL46 | polymer | 283 | 32175.7 | 1 | UniProt (Q9EQI8) Pfam (PF11788) | Mus musculus (house mouse) | 39S ribosomal protein L46,mitochondrial,L46mt,MRP-L46 |
| 58 | FB (p) | Large ribosomal subunit protein mL62 | polymer | 206 | 23519.0 | 1 | UniProt (Q8R035) Pfam (PF00472) | Mus musculus (house mouse) | 39S ribosomal protein L58,mitochondrial,MRP-L58,Immature colon carcinoma transcript 1 protein homolog,Peptidyl-tRNA hydrolase ICT1 |
| 59 | GB (t) | GTP-binding protein 10 | polymer | 366 | 40200.6 | 1 | UniProt (Q8K013) Pfam (PF01018) Pfam (PF01926) | Mus musculus (house mouse) | |
| 60 | AC, AD, AE, AF, BC... (A, M, O, R) | MAGNESIUM ION | non-polymer | 24.3 | 99 | Chemie (MG) | |||
| 61 | ZE (I) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 1 | Chemie (FES) | |||
| 62 | DF, FF (4, 0) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 63 | EF, GF (z, t) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 2 | Chemie (GNP) |
Sequence modifications
A: 1093 - 2676 (GenBank: 10336604)
X: 1 - 257 (UniProt: Q9D1B9)
X: 258 - 294 (UniProt: Q9DCI9)
| PDB | External Database | Details |
|---|---|---|
| U 1842 | C 1842 | conflict |
| A 2197 | U 2197 | conflict |
| A 2431 | G 2431 | conflict |
X: 258 - 294 (UniProt: Q9DCI9)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 59 |
| Total formula weight | 1950557.0 | |
| Non-Polymers* | Number of molecules | 104 |
| Total formula weight | 3757.2 | |
| All* | Total formula weight | 1954314.2 |
