9H9T
Crystal structure of NEDD4 HECT domain in complex with covalent inhibitor
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Isoform 4 of E3 ubiquitin-protein ligase NEDD4 | polymer | 375 | 44739.0 | 1 | UniProt (P46934) Pfam (PF00632) | Homo sapiens (human) | Cell proliferation-inducing gene 53 protein,HECT-type E3 ubiquitin transferase NEDD4,Neural precursor cell expressed developmentally down-regulated protein 4,NEDD-4 |
| 2 | B (A) | ethyl 4-[4-(2-chloranyl-5,6-dihydrobenzo[b][1]benzazepin-11-yl)butylamino]butanoate | non-polymer | 415.0 | 1 | Chemie (A1ITT) | |||
| 3 | C (A) | water | water | 18.0 | 107 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 44739.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 415.0 | |
| All* | Total formula weight | 45154.0 |
