9H5R

X-ray structure of Trichomonas vaginalis inactive mutant hydrogenosomal processing peptidase heterodimer (HPPin)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Alpha-MPP	polymer	431	47480.1	1	UniProt (A2D7B7) Pfam (PF05193)	Trichomonas vaginalis	alpha subunit of hydrogenosomal processing peptidase (HPP)
2	B (B)	Clan ME, family M16, insulinase-like metallopeptidase	polymer	419	46876.8	1	UniProt (A2ES04) Pfam (PF00675) Pfam (PF05193)	Trichomonas vaginalis	beta subunit of hydrogenosomal processing peptidase (HPP)
3	C, D, E, F, H... (A, B)	SULFATE ION	non-polymer		96.1	6	Chemie (SO4)
4	G (B)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
5	J, K (A, B)	water	water		18.0	67	Chemie (HOH)

Sequence modifications

A: 1 - 418 (UniProt: A2D7B7)

PDB	External Database	Details
Gly 240	Glu 240	conflict
Gly 419	-	expression tag
Ser 420	-	expression tag
Ala 421	-	expression tag
Leu 422	-	expression tag
Glu 423	-	expression tag
His 424	-	expression tag
His 425	-	expression tag
His 426	-	expression tag
His 427	-	expression tag
His 428	-	expression tag
His 429	-	expression tag
His 430	-	expression tag
His 431	-	expression tag

B: 1 - 419 (UniProt: A2ES04)

PDB	External Database	Details
Gln 56	Glu 56	engineered mutation
Ser 260	Pro 260	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	94356.9
Non-Polymers*	Number of molecules	7
	Total formula weight	641.8
All*	Total formula weight	94998.7

*Water molecules are not included.