9H5E

NNMT-SAH IN COMPLEX WITH 1p

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Nicotinamide N-methyltransferase	polymer	280	31326.6	6	UniProt (P40261) Pfam (PF01234)	Homo sapiens (human)
2	G, I, K, M, O... (A, B, C, D, E...)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	6	Chemie (SAH) PubChem (439155)
3	H, J, L, N, P... (A, B, C, D, E...)	6-methoxy-1-methyl-pyridine-3-carboxamide	non-polymer		167.2	6	Chemie (A1ISJ) PubChem (132471849)
4	S, T, U, V, W... (A, B, C, D, E...)	water	water		18.0	670	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 3 - 261 (UniProt: P40261)

PDB	External Database	Details
His -18	-	expression tag
Asn -17	-	expression tag
His -16	-	expression tag
Asn -15	-	expression tag
His -14	-	expression tag
Asn -13	-	expression tag
His -12	-	expression tag
Asn -11	-	expression tag
His -10	-	expression tag
Asn -9	-	expression tag
His -8	-	expression tag
Asn -7	-	expression tag
Ala -6	-	expression tag
Ala -5	-	expression tag
Ala -4	-	expression tag
Glu -3	-	expression tag
Asn -2	-	expression tag
Leu -1	-	expression tag
Tyr 0	-	expression tag
Phe 1	-	expression tag
Gln 2	-	expression tag
Ala 100	Lys 100	engineered mutation
Ala 101	Glu 101	engineered mutation
Ala 103	Glu 103	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	187959.7
Non-Polymers*	Number of molecules	12
	Total formula weight	3309.6
All*	Total formula weight	191269.3

*Water molecules are not included.