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9H44

Jumonji domain-containing protein 2B with crown ether and crystallization epitope mutations L916G:R917A:A918D

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Lysine-specific demethylase 4Bpolymer13214724.41UniProt (O94953)
Pfam (PF18104)
Homo sapiens (human)JmjC domain-containing histone demethylation protein 3B,Jumonji domain-containing protein 2B,[histone H3]-trimethyl-L-lysine(9) demethylase 4B
2B
(A)
1,4,7,10,13,16-HEXAOXACYCLOOCTADECANEnon-polymer264.31Chemie (O4B)
3C
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
4D
(A)
waterwater18.0106Chemie (HOH)
Sequence modifications
A: 915 - 1044 (UniProt: O94953)
PDBExternal DatabaseDetails
Ser 913-expression tag
Met 914-expression tag
Gly 916Leu 916engineered mutation
Ala 917Arg 917engineered mutation
Asp 918Ala 918engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight14724.4
Non-Polymers*Number of molecules2
Total formula weight299.8
All*Total formula weight15024.2
*Water molecules are not included.

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PDB entries from 2025-07-23

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