9H44
Jumonji domain-containing protein 2B with crown ether and crystallization epitope mutations L916G:R917A:A918D
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | Lysine-specific demethylase 4B | polymer | 132 | 14724.4 | 1 | UniProt (O94953) Pfam (PF18104) | Homo sapiens (human) | JmjC domain-containing histone demethylation protein 3B,Jumonji domain-containing protein 2B,[histone H3]-trimethyl-L-lysine(9) demethylase 4B |
2 | B (A) | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE | non-polymer | 264.3 | 1 | Chemie (O4B) | |||
3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
4 | D (A) | water | water | 18.0 | 106 | Chemie (HOH) |
Sequence modifications
A: 915 - 1044 (UniProt: O94953)
PDB | External Database | Details |
---|---|---|
Ser 913 | - | expression tag |
Met 914 | - | expression tag |
Gly 916 | Leu 916 | engineered mutation |
Ala 917 | Arg 917 | engineered mutation |
Asp 918 | Ala 918 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 14724.4 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 299.8 | |
All* | Total formula weight | 15024.2 |