9GZ2
Beta-cardiac heavy meromyosin motor domain in the primed state complexed to mavacamten
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Myosin-7 | polymer | 1145 | 131852.5 | 1 | UniProt (P12883) Pfam (PF02736) Pfam (PF00063) | Homo sapiens (human) | Myosin heavy chain 7,Myosin heavy chain slow isoform,MyHC-slow,Myosin heavy chain,cardiac muscle beta isoform,MyHC-beta |
| 2 | B (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | C (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 4 | D (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 5 | E (A) | Mavacamten | non-polymer | 273.3 | 1 | Chemie (XB2) |
Sequence modifications
A: 2 - 1138 (UniProt: P12883)
| PDB | External Database | Details |
|---|---|---|
| Ser 1124 | Ala 1124 | variant |
| Asp 1139 | - | expression tag |
| Tyr 1140 | - | expression tag |
| Lys 1141 | - | expression tag |
| Asp 1142 | - | expression tag |
| Asp 1143 | - | expression tag |
| Asp 1144 | - | expression tag |
| Asp 1145 | - | expression tag |
| Lys 1146 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 131852.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 819.8 | |
| All* | Total formula weight | 132672.3 |
