9GXE
Structure of the SARS-CoV spike glycoprotein in complex with a homotrimeric Bicycle molecule
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Spike glycoprotein | polymer | 1133 | 125519.1 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) | Severe acute respiratory syndrome coronavirus 2 | S glycoprotein,E2,Peplomer protein |
| 2 | D, E, F (D, E, F) | Homotrimeric bicycle molecule | polymer | 16 | 1507.9 | 3 | synthetic construct | ||
| 3 | G, H, I, J, K... (AA, AB, AC, BA, BB...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 9 | In PDB GlyTouCan (G42666HT) | |||
| 4 | AA, BA, CA, DA, EA... (B, C, A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 21 | Chemie (NAG) | |||
| 5 | FA, MA, W (B, C, A) | STEARIC ACID | non-polymer | 284.5 | 3 | Chemie (STE) | |||
| 6 | NA, OA, PA (D, E, F) | 2,4,6-tris(chloromethyl)-1,3,5-triazine | non-polymer | 226.5 | 3 | Chemie (KZ0) | |||
| 7 | QA, RA, SA (A, B, C) | water | water | 18.0 | 139 | Chemie (HOH) |
Sequence modifications
A, B, C: 14 - 1146 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Pro 817 | Phe 817 | engineered mutation |
| Pro 892 | Ala 892 | engineered mutation |
| Pro 899 | Ala 899 | engineered mutation |
| Pro 942 | Ala 942 | engineered mutation |
| Pro 986 | Lys 986 | engineered mutation |
| Pro 987 | Val 987 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 381081.0 | |
| Branched | Number of molecules | 9 |
| Total formula weight | 3819.6 | |
| Non-Polymers* | Number of molecules | 27 |
| Total formula weight | 6178.3 | |
| All* | Total formula weight | 391078.9 |
