9GWT
crystal structure of 23ME-00610 Fab in complex with human CD200R1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | 23ME-00610 Fab (heavy) | polymer | 234 | 24980.1 | 1 | Homo sapiens | 23ME-00610 Fab | |
| 2 | B (L) | 23ME-00610 Fab (light) | polymer | 218 | 23887.4 | 1 | Homo sapiens | 23ME-00610 Fab | |
| 3 | C (P) | Isoform 1 of Cell surface glycoprotein CD200 receptor 1 | polymer | 268 | 29883.0 | 1 | UniProt (Q8TD46) Pfam (PF08205) | Homo sapiens (human) | CD200 cell surface glycoprotein receptor,Cell surface glycoprotein OX2 receptor 1 |
| 4 | D, H (A, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 5 | E (B) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 6 | F (C) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1235.1 | 1 | In PDB GlyTouCan (G55220VL) | |||
| 7 | G (D) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G22573RC) | |||
| 8 | I (L) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 9 | J, K, L (H, L, P) | water | water | 18.0 | 25 | Chemie (HOH) |
Sequence modifications
P: 29 - 243 (UniProt: Q8TD46)
| PDB | External Database | Details |
|---|---|---|
| Met 10 | - | initiating methionine |
| Gly 11 | - | expression tag |
| Trp 12 | - | expression tag |
| Ser 13 | - | expression tag |
| Cys 14 | - | expression tag |
| Ile 15 | - | expression tag |
| Ile 16 | - | expression tag |
| Leu 17 | - | expression tag |
| Phe 18 | - | expression tag |
| Leu 19 | - | expression tag |
| Val 20 | - | expression tag |
| Ala 21 | - | expression tag |
| Thr 22 | - | expression tag |
| Ala 23 | - | expression tag |
| Thr 24 | - | expression tag |
| Gly 25 | - | expression tag |
| Val 26 | - | expression tag |
| His 27 | - | expression tag |
| Ser 28 | - | expression tag |
| Gly 244 | - | expression tag |
| Gly 245 | - | expression tag |
| Gly 246 | - | expression tag |
| Ser 247 | - | expression tag |
| Gly 248 | - | expression tag |
| Leu 249 | - | expression tag |
| Asn 250 | - | expression tag |
| Asp 251 | - | expression tag |
| Ile 252 | - | expression tag |
| Phe 253 | - | expression tag |
| Glu 254 | - | expression tag |
| Ala 255 | - | expression tag |
| Gln 256 | - | expression tag |
| Lys 257 | - | expression tag |
| Ile 258 | - | expression tag |
| Glu 259 | - | expression tag |
| Trp 260 | - | expression tag |
| His 261 | - | expression tag |
| Glu 262 | - | expression tag |
| Gly 263 | - | expression tag |
| Gly 264 | - | expression tag |
| Ser 265 | - | expression tag |
| Gly 266 | - | expression tag |
| Ser 267 | - | expression tag |
| Gly 268 | - | expression tag |
| Thr 269 | - | expression tag |
| His 270 | - | expression tag |
| His 271 | - | expression tag |
| His 272 | - | expression tag |
| His 273 | - | expression tag |
| His 274 | - | expression tag |
| His 275 | - | expression tag |
| His 276 | - | expression tag |
| His 277 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 78750.4 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 3419.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 92.1 | |
| All* | Total formula weight | 82261.6 |
