9GW5

type-I interferon autoantibodies pmab3, pmab19 and pmab14 in complex with Interferon alpha-2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Interferon alpha-2	polymer	188	21581.5	1	UniProt (P01563) Pfam (PF00143)	Homo sapiens (human)	IFN-alpha-2,Interferon alpha-A,LeIF A
2	B (H)	type-I interferons autoantibody pamb14 heavy chain	polymer	290	30180.0	1		Homo sapiens
3	C (U)	scFv type-I interferons autoantibody pamb03	polymer	288	30131.9	1		Homo sapiens
4	D (V)	scFv type-I interferons autoantibody pamb19	polymer	285	29945.9	1		Homo sapiens

Sequence modifications

A: 1 - 165 (UniProt: P01563)

PDB	External Database	Details
Gly 166	-	expression tag
Gly 167	-	expression tag
Gly 168	-	expression tag
Gly 169	-	expression tag
Ser 170	-	expression tag
Leu 171	-	expression tag
Val 172	-	expression tag
Pro 173	-	expression tag
Arg 174	-	expression tag
Gly 175	-	expression tag
Ser 176	-	expression tag
Gly 177	-	expression tag
Gly 178	-	expression tag
Gly 179	-	expression tag
Ser 180	-	expression tag
His 181	-	expression tag
His 182	-	expression tag
His 183	-	expression tag
His 184	-	expression tag
His 185	-	expression tag
His 186	-	expression tag
His 187	-	expression tag
His 188	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	111839.3
All*	Total formula weight	111839.3

*Water molecules are not included.