9GVL

type-I interferons autoantibody pmab15 in complex with Interferon alpha-2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Interferon alpha-2	polymer	188	21581.5	2	UniProt (P01563) Pfam (PF00143)	Homo sapiens (human)	IFN-alpha-2,Interferon alpha-A,LeIF A
2	C, D (H, I)	scFv type-I interferons autoantibody pmab15	polymer	294	30802.3	2		Homo sapiens
3	E (B)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
4	F, G, H (B, H, I)	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
5	I, J, K, L (A, B, H, I)	water	water		18.0	287	Chemie (HOH)

Sequence modifications

A, B: 1 - 165 (UniProt: P01563)

PDB	External Database	Details
Gly 166	-	expression tag
Gly 167	-	expression tag
Gly 168	-	expression tag
Gly 169	-	expression tag
Ser 170	-	expression tag
Leu 171	-	expression tag
Val 172	-	expression tag
Pro 173	-	expression tag
Arg 174	-	expression tag
Gly 175	-	expression tag
Ser 176	-	expression tag
Gly 177	-	expression tag
Gly 178	-	expression tag
Gly 179	-	expression tag
Ser 180	-	expression tag
His 181	-	expression tag
His 182	-	expression tag
His 183	-	expression tag
His 184	-	expression tag
His 185	-	expression tag
His 186	-	expression tag
His 187	-	expression tag
His 188	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	104767.7
Non-Polymers*	Number of molecules	4
	Total formula weight	380.3
All*	Total formula weight	105148.0

*Water molecules are not included.