9GV3

Crystal structure of the complex between Nb474 mutant R53A,D125A and Trypanosoma congolense fructose-1,6-bisphosphate aldolase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Fructose-bisphosphate aldolase	polymer	387	42708.6	4	UniProt (G0UWE7) Pfam (PF00274)	Trypanosoma congolense IL3000
2	E, F, G, H (E, F, G, H)	Nb474 mutant R53A,D125A	polymer	143	15670.0	4		Vicugna pacos
3	I, J, K, L (B, C)	ACETATE ION	non-polymer		59.0	4	Chemie (ACT)
4	M (D)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
5	N, O, P, Q, R... (A, B, C, D, E...)	water	water		18.0	1343	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 372 (UniProt: G0UWE7)

PDB	External Database	Details
Glu 373	-	expression tag
Asn 374	-	expression tag
Leu 375	-	expression tag
Tyr 376	-	expression tag
Phe 377	-	expression tag
Gln 378	-	expression tag
Ser 379	-	expression tag
Gly 380	-	expression tag
Gly 381	-	expression tag
His 382	-	expression tag
His 383	-	expression tag
His 384	-	expression tag
His 385	-	expression tag
His 386	-	expression tag
His 387	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	233514.3
Non-Polymers*	Number of molecules	5
	Total formula weight	328.3
All*	Total formula weight	233842.6

*Water molecules are not included.