9GTE
Crystal structure of TRIM21 PRY-SPRY domain bound to Suramin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | E3 ubiquitin-protein ligase TRIM21 | polymer | 188 | 21596.4 | 1 | UniProt (Q62191) Pfam (PF13765) Pfam (PF00622) | Mus musculus (house mouse) | 52 kDa Ro protein,52 kDa ribonucleoprotein autoantigen Ro/SS-A,Ro(SS-A),Sjoegren syndrome type A antigen,SS-A,Tripartite motif-containing protein 21 |
| 2 | B, C, D, E, F... (B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 3 | H (B) | 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID | non-polymer | 1297.3 | 1 | Chemie (SVR) | |||
| 4 | I (B) | water | water | 18.0 | 151 | Chemie (HOH) |
Sequence modifications
B: 291 - 470 (UniProt: Q62191)
| PDB | External Database | Details |
|---|---|---|
| Met 283 | - | initiating methionine |
| His 284 | - | expression tag |
| His 285 | - | expression tag |
| His 286 | - | expression tag |
| His 287 | - | expression tag |
| His 288 | - | expression tag |
| His 289 | - | expression tag |
| Met 290 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 21596.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1669.7 | |
| All* | Total formula weight | 23266.0 |
