9GST
LN02-ML85 Fab in complex with crosslinked DS-SOSIP HIV-1 Env trimer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, C, E) | Envelope glycoprotein gp160 | polymer | 481 | 54086.3 | 3 | UniProt (A0A6H1VH54) | Human immunodeficiency virus 1 | Env polyprotein |
| 2 | B, D, F (B, D, F) | Envelope glycoprotein gp160 | polymer | 161 | 18143.5 | 3 | UniProt (A0A6H1VGP3) | Human immunodeficiency virus 1 | Env polyprotein |
| 3 | G (H) | Heavy chain Fab of antibody LN02-ML85 | polymer | 224 | 23790.0 | 1 | Homo sapiens | ||
| 4 | H (L) | Light chain of antibody LN02-ML85 | polymer | 214 | 22975.4 | 1 | Homo sapiens | ||
| 5 | BA, CA, DA, EA, GA... (b, c, d, e, g...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 25 | In PDB GlyTouCan (G42666HT) | |||
| 6 | Q (Q) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G42227JK) | |||
| 7 | AA (a) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
| 8 | FA (f) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 9 | AB, BB, CB, DB, EB... (D, E, A, F, B...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 29 | Chemie (NAG) |
Sequence modifications
A, C, E: 31 - 511 (UniProt: A0A6H1VH54)
B, D, F: 512 - 666 (UniProt: A0A6H1VGP3)
| PDB | External Database | Details |
|---|---|---|
| Cys 201 | Ile 200 | conflict |
| Ser 375 | Tyr 373 | conflict |
| Cys 433 | Ala 430 | conflict |
| Cys 501 | Ala 498 | conflict |
| Arg 509 | Glu 506 | conflict |
| Arg 512 | - | expression tag |
| Arg 513 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Pro 559 | Ile 555 | conflict |
| Cys 605 | Thr 601 | conflict |
| Asp 665 | Lys 661 | conflict |
| Tyr 666 | Trp 662 | conflict |
| Lys 667 | - | expression tag |
| Asp 668 | - | expression tag |
| Asp 669 | - | expression tag |
| Asp 670 | - | expression tag |
| Asp 671 | - | expression tag |
| Lys 672 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 263454.8 | |
| Branched | Number of molecules | 28 |
| Total formula weight | 13180.4 | |
| Non-Polymers* | Number of molecules | 29 |
| Total formula weight | 6415.0 | |
| All* | Total formula weight | 283050.2 |
