9GS4
SARS-CoV-2 methyltransferase nsp10-16 in complex with SAM and theophylline derivative LAS 54571130
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 2'-O-methyltransferase nsp16 | polymer | 301 | 33711.6 | 1 | UniProt (P0DTD1) Pfam (PF06460) | Severe acute respiratory syndrome coronavirus 2 | pp1ab,ORF1ab polyprotein |
| 2 | B (B) | Non-structural protein 10 | polymer | 115 | 12271.0 | 1 | UniProt (P0DTD1) Pfam (PF09401) | Severe acute respiratory syndrome coronavirus 2 | pp1ab,ORF1ab polyprotein |
| 3 | C, D, F, G, H... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 16 | Chemie (EDO) | |||
| 4 | E (A) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) PubChem (4478249) | |||
| 5 | L, T (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) PubChem (923) | |||
| 6 | R (A) | ~{N}-[(5~{S})-5-azanyl-6-[(3~{S},4~{S},6~{R})-3-[1,3-dimethyl-2,6-bis(oxidanylidene)purin-7-yl]-4-methyl-4,6-bis(oxidanyl)azepan-1-yl]-6-oxidanylidene-hexyl]ethanamide | non-polymer | 493.6 | 1 | Chemie (A1IOL) PubChem (129587793) PubChem (129587800) | |||
| 7 | S (A) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) PubChem (5136) PubChem (34755) PubChem (9865603) PubChem (12312798) PubChem (58766358) PubChem (87224684) PubChem (131697735) PubChem (145712080) PubChem (58633578) PubChem (60038769) PubChem (73897310) PubChem (132988922) PubChem (134692588) PubChem (135030730) PubChem (140459785) PubChem (163046094) | |||
| 8 | U, V (B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 9 | Z (B) | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 10 | AA, BA (A, B) | water | water | 18.0 | 228 | Chemie (HOH) |
Sequence modifications
A: 6799 - 7096 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Glu 7097 | - | expression tag |
| Asn 7098 | - | expression tag |
| Leu 7099 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 45982.7 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 2326.2 | |
| All* | Total formula weight | 48308.9 |
