9GS4
SARS-CoV-2 methyltransferase nsp10-16 in complex with SAM and theophylline derivative LAS 54571130
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 2'-O-methyltransferase nsp16 | polymer | 301 | 33711.6 | 1 | UniProt (P0DTD1) Pfam (PF06460) | Severe acute respiratory syndrome coronavirus 2 | pp1ab,ORF1ab polyprotein |
| 2 | B (B) | Non-structural protein 10 | polymer | 115 | 12271.0 | 1 | UniProt (P0DTD1) Pfam (PF09401) | Severe acute respiratory syndrome coronavirus 2 | pp1ab,ORF1ab polyprotein |
| 3 | C, D, F, G, H... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 16 | Chemie (EDO) | |||
| 4 | E (A) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 5 | L, T (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 6 | R (A) | ~{N}-[(5~{S})-5-azanyl-6-[(3~{S},4~{S},6~{R})-3-[1,3-dimethyl-2,6-bis(oxidanylidene)purin-7-yl]-4-methyl-4,6-bis(oxidanyl)azepan-1-yl]-6-oxidanylidene-hexyl]ethanamide | non-polymer | 493.6 | 1 | Chemie (A1IOL) | |||
| 7 | S (A) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) | |||
| 8 | U, V (B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 9 | Z (B) | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 10 | AA, BA (A, B) | water | water | 18.0 | 228 | Chemie (HOH) |
Sequence modifications
A: 6799 - 7096 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Glu 7097 | - | expression tag |
| Asn 7098 | - | expression tag |
| Leu 7099 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 45982.7 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 2326.2 | |
| All* | Total formula weight | 48308.9 |
