9GQP
Structural characterization of a N-acetyl-beta-neuraminic acid-binding site in human RNase2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Non-secretory ribonuclease | polymer | 135 | 15611.8 | 1 | UniProt (P10153) Pfam (PF00074) | Homo sapiens (Human) | Eosinophil-derived neurotoxin,RNase UpI-2,Ribonuclease 2,RNase 2,Ribonuclease US |
| 2 | B, C, D, G (A) | N-acetyl-beta-neuraminic acid | non-polymer | 309.3 | 4 | Chemie (SLB) PubChem (445063) | |||
| 3 | E (A) | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 282.3 | 1 | Chemie (B3P) PubChem (125132) | |||
| 4 | F (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) PubChem (175) | |||
| 5 | H (A) | water | water | 18.0 | 250 | Chemie (HOH) |
Sequence modifications
A: 1 - 134 (UniProt: P10153)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15611.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1578.5 | |
| All* | Total formula weight | 17190.2 |
