9GQP
Structural characterization of a N-acetyl-beta-neuraminic acid-binding site in human RNase2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Non-secretory ribonuclease | polymer | 135 | 15611.8 | 1 | UniProt (P10153) Pfam (PF00074) | Homo sapiens (Human) | Eosinophil-derived neurotoxin,RNase UpI-2,Ribonuclease 2,RNase 2,Ribonuclease US |
| 2 | B, C, D, G (A) | N-acetyl-beta-neuraminic acid | non-polymer | 309.3 | 4 | Chemie (SLB) PubChem (16758151) PubChem (17757261) PubChem (20843074) PubChem (1807423) PubChem (906) PubChem (8565) PubChem (163606) PubChem (24801877) PubChem (439197) PubChem (26470719) PubChem (26470725) PubChem (36690637) PubChem (40429907) PubChem (40477531) PubChem (40785048) PubChem (42553514) PubChem (42553516) PubChem (42553518) PubChem (42553520) PubChem (44120039) PubChem (444885) PubChem (445063) PubChem (445727) PubChem (44338934) PubChem (45933901) PubChem (26470722) PubChem (49819355) PubChem (1549084) PubChem (57859521) PubChem (58341444) PubChem (58545373) PubChem (58964108) PubChem (59331136) PubChem (58392620) PubChem (67604154) PubChem (68257483) PubChem (68260278) PubChem (68315779) PubChem (70643192) PubChem (70666785) PubChem (70979316) PubChem (71299579) PubChem (71650744) PubChem (5748928) PubChem (6398955) PubChem (6992095) PubChem (7059665) PubChem (7092680) PubChem (7092682) PubChem (7173826) PubChem (89869240) PubChem (89869500) PubChem (89869501) PubChem (89869502) PubChem (7569151) PubChem (656387) PubChem (92354618) PubChem (10936453) PubChem (11370291) PubChem (11876108) PubChem (11908614) PubChem (93959067) PubChem (94016791) PubChem (95566316) PubChem (96562275) PubChem (13657114) PubChem (15560306) PubChem (15560307) PubChem (15560308) PubChem (15560310) PubChem (15560312) PubChem (15560313) PubChem (15560315) PubChem (15560316) PubChem (15560317) PubChem (5702294) PubChem (6560217) PubChem (102004932) PubChem (7048542) PubChem (7173829) PubChem (102145501) PubChem (117937408) PubChem (122374560) PubChem (124040735) PubChem (124490223) PubChem (126963458) PubChem (129672250) PubChem (130267610) PubChem (130330497) PubChem (132187635) PubChem (145832226) PubChem (15560314) PubChem (133688898) PubChem (134689626) PubChem (134973249) PubChem (135053795) PubChem (135055138) PubChem (139256539) PubChem (168364984) PubChem (155021572) PubChem (156051160) PubChem (160911533) PubChem (160911534) PubChem (164670778) PubChem (166985445) PubChem (168314628) PubChem (168358112) PubChem (168358795) PubChem (168369824) PubChem (168370581) PubChem (168373659) PubChem (168375635) PubChem (173875492) PubChem (173910549) PubChem (173918449) | |||
| 3 | E (A) | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 282.3 | 1 | Chemie (B3P) PubChem (125132) | |||
| 4 | F (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) PubChem (175) | |||
| 5 | H (A) | water | water | 18.0 | 250 | Chemie (HOH) |
Sequence modifications
A: 1 - 134 (UniProt: P10153)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15611.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1578.5 | |
| All* | Total formula weight | 17190.2 |
