9GOY

Crystal structure of Fab E2-RecA in complex with CD38

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	polymer	264	30781.8	1	UniProt (P28907) Pfam (PF02267)	Homo sapiens (human)	2'-phospho-ADP-ribosyl cyclase,2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase,2'-phospho-cyclic-ADP-ribose transferase,ADP-ribosyl cyclase 1,ADPRC 1,Cyclic ADP-ribose hydrolase 1,cADPR hydrolase 1,T10
2	B (H)	Fab E2-RecA heavy chain	polymer	226	24100.1	1		Homo sapiens
3	C (L)	Fab E2-RecA light chain	polymer	214	23415.0	1		Homo sapiens
4	D, E (A)	POTASSIUM ION	non-polymer		39.1	2	Chemie (K)
5	F, G (A, L)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
6	H, I, J (A, H, L)	water	water		18.0	81	Chemie (HOH)

Sequence modifications

A: 45 - 300 (UniProt: P28907)

PDB	External Database	Details
Asp 100	Asn 100	engineered mutation
Ala 164	Asn 164	engineered mutation
Asp 209	Asn 209	engineered mutation
Asp 219	Asn 219	engineered mutation
His 301	-	expression tag
His 302	-	expression tag
His 303	-	expression tag
His 304	-	expression tag
His 305	-	expression tag
His 306	-	expression tag
His 307	-	expression tag
His 308	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	78296.9
Non-Polymers*	Number of molecules	4
	Total formula weight	149.1
All*	Total formula weight	78446.0

*Water molecules are not included.