9GOX

Crystal structure of Fab B6-D9 in complex with CD38

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (H)	Fab B6-D9 heavy chain	polymer	224	23968.9	1		Homo sapiens
2	B (L)	Fab B6-D9 light chain	polymer	214	23415.0	1		Homo sapiens
3	C (A)	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	polymer	264	30821.9	1	UniProt (P28907) Pfam (PF02267)	Homo sapiens (human)	2'-phospho-ADP-ribosyl cyclase,2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase,2'-phospho-cyclic-ADP-ribose transferase,ADP-ribosyl cyclase 1,ADPRC 1,Cyclic ADP-ribose hydrolase 1,cADPR hydrolase 1,T10
4	D, K (H, A)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
5	E, F, G, L, M... (H, L, A)	1,2-ETHANEDIOL	non-polymer		62.1	9	Chemie (EDO)
6	H, I, J (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)
7	N (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
8	Q (A)	ACETATE ION	non-polymer		59.0	1	Chemie (ACT)
9	T (A)	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID	non-polymer		238.3	1	Chemie (EPE)
10	U, V, W (H, L, A)	water	water		18.0	696	Chemie (HOH)

Sequence modifications

A: 45 - 300 (UniProt: P28907)

PDB	External Database	Details
His 301	-	expression tag
His 302	-	expression tag
His 303	-	expression tag
His 304	-	expression tag
His 305	-	expression tag
His 306	-	expression tag
His 307	-	expression tag
His 308	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	78205.8
Non-Polymers*	Number of molecules	17
	Total formula weight	1803.8
All*	Total formula weight	80009.6

*Water molecules are not included.