9GOW
Crystal structure of phosphorylated human IRE1a in complex with IA107
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Serine/threonine-protein kinase/endoribonuclease IRE1 | polymer | 434 | 49744.4 | 4 | UniProt (O75460) Pfam (PF00069) Pfam (PF06479) | Homo sapiens (human) | Endoplasmic reticulum-to-nucleus signaling 1,Inositol-requiring protein 1,hIRE1p,Ire1-alpha,IRE1a |
| 2 | E, F, G, H (A, B, C, D) | 3-[5-bromanyl-2-methyl-1-(phenylcarbonyl)indol-3-yl]propanoic acid | non-polymer | 386.2 | 4 | Chemie (A1IOO) PubChem (176730552) |
Sequence modifications
A, B, C, D: 547 - 977 (UniProt: O75460)
| PDB | External Database | Details |
|---|---|---|
| Gly 544 | - | expression tag |
| Gly 545 | - | expression tag |
| Ser 546 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 198977.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1545.0 | |
| All* | Total formula weight | 200522.5 |
