9GOP
Crystal structure of CDK2-cyclin E1 bound by compound 30
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cyclin-dependent kinase 2 | polymer | 298 | 33976.5 | 1 | UniProt (P24941) Pfam (PF00069) | Homo sapiens (human) | Cell division protein kinase 2,p33 protein kinase |
| 2 | B (B) | G1/S-specific cyclin-E1 | polymer | 285 | 33053.5 | 1 | UniProt (P24864) Pfam (PF00134) Pfam (PF02984) | Homo sapiens (human) | |
| 3 | C (A) | 2-[(2~{S})-1-[9-ethyl-6-[(2-methyl-5-methylsulfonyl-pyrazol-3-yl)amino]purin-2-yl]-4,4-bis(fluoranyl)pyrrolidin-2-yl]propan-2-ol | non-polymer | 484.5 | 1 | Chemie (A1IOI) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 120 | Chemie (HOH) |
Sequence modifications
B: 81 - 363 (UniProt: P24864)
| PDB | External Database | Details |
|---|---|---|
| Gly 79 | - | expression tag |
| Ser 80 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 67030.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 484.5 | |
| All* | Total formula weight | 67514.5 |
