9GOD
Crystal structure of DPP9 in complex with N-phosphono-(S)-3-aminopiperidine-2-one-based inhibitor
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Dipeptidyl peptidase 9 | polymer | 851 | 97523.5 | 4 | UniProt (Q86TI2) Pfam (PF19520) Pfam (PF00930) Pfam (PF00326) | Homo sapiens (human) | DP9,Dipeptidyl peptidase IV-related protein 2,DPRP-2,Dipeptidyl peptidase IX,DPP IX,Dipeptidyl peptidase-like protein 9,DPLP9 |
| 2 | CA, E, P, PA (C, A, B, D) | ethoxy-[2-(4-pentylphenyl)sulfanylethyl]phosphinous acid | non-polymer | 300.4 | 4 | Chemie (A1INH) | |||
| 3 | AA, BA, DA, EA, F... (B, C, A, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 35 | Chemie (EDO) | |||
| 4 | O, OA (A, C) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | TA, UA, VA, WA (A, B, C, D) | water | water | 18.0 | 636 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 20 - 863 (UniProt: Q86TI2)
| PDB | External Database | Details |
|---|---|---|
| Met 19 | - | initiating methionine |
| His 864 | - | expression tag |
| His 865 | - | expression tag |
| His 866 | - | expression tag |
| His 867 | - | expression tag |
| His 868 | - | expression tag |
| His 869 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 390094.1 | |
| Non-Polymers* | Number of molecules | 41 |
| Total formula weight | 3444.9 | |
| All* | Total formula weight | 393538.9 |
