9GNY
SARS-CoV-2 methyltransferase nsp10-16 in complex with SAM and Caffeine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 2'-O-methyltransferase nsp16 | polymer | 304 | 34150.1 | 1 | UniProt (P0DTD1) Pfam (PF06460) | Severe acute respiratory syndrome coronavirus 2 | Non-structural protein 16,nsp16 |
| 2 | B (B) | Non-structural protein 10 | polymer | 140 | 14860.0 | 1 | UniProt (P0DTD1) Pfam (PF09401) | Severe acute respiratory syndrome coronavirus 2 | nsp10,Growth factor-like peptide,GFL |
| 3 | BA, C, CA, D, F... (B, A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 20 | Chemie (EDO) | |||
| 4 | E (A) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 5 | R (A) | CAFFEINE | non-polymer | 194.2 | 1 | Chemie (CFF) | |||
| 6 | S (A) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) | |||
| 7 | T (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 8 | V, W (B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 9 | AA (B) | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 10 | DA, EA (A, B) | water | water | 18.0 | 328 | Chemie (HOH) |
Sequence modifications
A: 6799 - 7096 (UniProt: P0DTD1)
B: 4254 - 4392 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Glu 7097 | - | expression tag |
| Asn 7098 | - | expression tag |
| Leu 7099 | - | expression tag |
| Tyr 7100 | - | expression tag |
| Phe 7101 | - | expression tag |
| Gln 7102 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 4253 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 49010.1 | |
| Non-Polymers* | Number of molecules | 27 |
| Total formula weight | 2264.6 | |
| All* | Total formula weight | 51274.7 |
