9GMY
Tubulin in complex with an oxathiane analog of zampanolide
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Tubulin alpha-1B chain | polymer | 451 | 50204.4 | 2 | UniProt (P81947) Pfam (PF00091) Pfam (PF03953) | Bos taurus (domestic cattle) | Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain |
| 2 | B, D (B, D) | Tubulin beta-2B chain | polymer | 445 | 49999.9 | 2 | UniProt (Q6B856) Pfam (PF00091) Pfam (PF03953) | Bos taurus (domestic cattle) | |
| 3 | E (E) | Stathmin-4 | polymer | 189 | 22125.3 | 1 | UniProt (P63043) Pfam (PF00836) | Rattus norvegicus (Norway rat) | Stathmin-like protein B3,RB3 |
| 4 | F (F) | Tubulin tyrosine ligase | polymer | 384 | 44378.5 | 1 | UniProt (A0A8V0Z8P0) Pfam (PF03133) | Gallus gallus (chicken) | |
| 5 | G, R (A, C) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
| 6 | H, M, S, W, Z (A, B, C, D, F) | MAGNESIUM ION | non-polymer | 24.3 | 5 | Chemie (MG) | |||
| 7 | I, P, T (A, B, C) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 8 | J (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 9 | K, N (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 10 | L, V (B, D) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
| 11 | O (B) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 12 | Q, X (B, D) | (2Z,4E)-N-[(S)-[(1R,2E,5S,8E,10Z,17S)-3,11-dimethyl-7,13-bis(oxidanylidene)-6,21-dioxa-19-thiabicyclo[15.3.1]henicosa-2,8,10-trien-5-yl]-oxidanyl-methyl]hexa-2,4-dienamide | non-polymer | 503.7 | 2 | Chemie (A1IM9) | |||
| 13 | U (C) | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 14 | Y (F) | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | non-polymer | 505.2 | 1 | Chemie (ACP) | |||
| 15 | AA, BA, CA, DA, EA... (A, B, C, D, E...) | water | water | 18.0 | 1294 | Chemie (HOH) |
Sequence modifications
F: 1 - 378 (UniProt: A0A8V0Z8P0)
| PDB | External Database | Details |
|---|---|---|
| - | Ala 53 | deletion |
| - | Glu 54 | deletion |
| - | Met 55 | deletion |
| - | Gln 56 | deletion |
| - | Gln 57 | deletion |
| - | Gln 58 | deletion |
| - | Leu 59 | deletion |
| - | Leu 60 | deletion |
| - | Glu 61 | deletion |
| - | Gly 62 | deletion |
| - | Asp 63 | deletion |
| - | Gln 64 | deletion |
| - | Thr 65 | deletion |
| - | Leu 66 | deletion |
| - | Val 67 | deletion |
| - | Leu 68 | deletion |
| - | Ala 69 | deletion |
| - | Ser 70 | deletion |
| - | Ser 71 | deletion |
| - | Thr 72 | deletion |
| - | His 73 | deletion |
| - | Pro 74 | deletion |
| - | Glu 75 | deletion |
| - | Ser 76 | deletion |
| - | Val 77 | deletion |
| - | Asp 78 | deletion |
| - | Ser 79 | deletion |
| - | Asp 80 | deletion |
| - | Lys 81 | deletion |
| - | Asn 82 | deletion |
| - | His 83 | deletion |
| - | Gly 84 | deletion |
| - | Phe 85 | deletion |
| His 379 | - | expression tag |
| His 380 | - | expression tag |
| His 381 | - | expression tag |
| His 382 | - | expression tag |
| His 383 | - | expression tag |
| His 384 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 266912.5 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 4171.0 | |
| All* | Total formula weight | 271083.5 |
