9GMU
Structure ofhuman aM ligand binding domain in complex with the aCR3 nanobody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Integrin alpha-M | polymer | 198 | 22480.6 | 2 | UniProt (P11215) Pfam (PF00092) | Homo sapiens (human) | CD11 antigen-like family member B,CR-3 alpha chain,Cell surface glycoprotein MAC-1 subunit alpha,Leukocyte adhesion receptor MO1,Neutrophil adherence receptor |
| 2 | C, D (C, D) | aCR VHH | polymer | 130 | 14453.9 | 2 | Lama glama | ||
| 3 | E, F (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | G, H (C, D) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A, B: 129 - 321 (UniProt: P11215)
| PDB | External Database | Details |
|---|---|---|
| Gly 124 | - | expression tag |
| Ala 125 | - | expression tag |
| Met 126 | - | expression tag |
| Gly 127 | - | expression tag |
| Ser 128 | - | expression tag |
| Gly 316 | Ile 332 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 73868.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 240.7 | |
| All* | Total formula weight | 74109.6 |
