9GKM
Structure of HECT E3 TRIP12 forming K29/K48-branched Ubiquitin chains
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Ubiquitin | polymer | 75 | 8519.8 | 1 | UniProt (P0CG48) Pfam (PF00240) | Homo sapiens (human) | |
| 2 | B (C) | Polyubiquitin-C | polymer | 76 | 8550.8 | 1 | UniProt (P0CG48) Pfam (PF00240) | Homo sapiens (human) | |
| 3 | C (D) | Polyubiquitin-B | polymer | 76 | 8604.8 | 1 | UniProt (P0CG47) Pfam (PF00240) UniProt (by SIFTS) (P0CG48) | Homo sapiens (human) | |
| 4 | D (A) | Isoform 3 of E3 ubiquitin-protein ligase TRIP12 | polymer | 1565 | 175752.5 | 1 | UniProt (Q14669) Pfam (PF00632) | Homo sapiens (human) | E3 ubiquitin-protein ligase for Arf,ULF,HECT-type E3 ubiquitin transferase TRIP12,Thyroid receptor-interacting protein 12,TR-interacting protein 12,TRIP-12 |
| 5 | E (B) | 5-azanylpentan-2-one | non-polymer | 101.1 | 1 | Chemie (SY8) |
Sequence modifications
C: 1 - 76 (UniProt: P0CG48)
D: 1 - 76 (UniProt: P0CG47)
A: 478 - 2040 (UniProt: Q14669)
| PDB | External Database | Details |
|---|---|---|
| Cys 29 | Lys 29 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Arg 48 | Lys 48 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 476 | - | expression tag |
| Ser 477 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 201427.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 101.1 | |
| All* | Total formula weight | 201529.0 |
