9GIW
Structure of the human mitochondrial pyruvate carrier inhibited by zaprinast
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitochondrial pyruvate carrier 1-like protein | polymer | 136 | 15155.5 | 1 | UniProt (P0DKB6) Pfam (PF03650) | Homo sapiens (human) | |
| 2 | B (B) | Mitochondrial pyruvate carrier 2 | polymer | 133 | 15093.7 | 1 | UniProt (O95563) Pfam (PF03650) | Homo sapiens (human) | Brain protein 44 |
| 3 | C (C) | Nanobody,Maltose/maltodextrin-binding periplasmic protein | polymer | 515 | 56307.0 | 1 | UniProt (P0AEY0) Pfam (PF01547) | synthetic construct | MMBP,Maltodextrin-binding protein,Maltose-binding protein,MBP |
| 4 | D (B) | 5-(2-propoxyphenyl)-3,4-dihydro-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | non-polymer | 271.3 | 1 | Chemie (A1IL3) |
Sequence modifications
B: 1 - 127 (UniProt: O95563)
C: 1 - 129 (PDB: 9GIW)
C: 132 - 491 (UniProt: P0AEY0)
| PDB | External Database | Details |
|---|---|---|
| Glu 128 | - | expression tag |
| Asn 129 | - | expression tag |
| Leu 130 | - | expression tag |
| Tyr 131 | - | expression tag |
| Phe 132 | - | expression tag |
| Gln 133 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Pro 130 | - | linker |
| Pro 131 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Pro 492 | - | expression tag |
| Gly 493 | - | expression tag |
| Ser 494 | - | expression tag |
| Pro 495 | - | expression tag |
| Asp 496 | - | expression tag |
| Ala 497 | - | expression tag |
| Ala 498 | - | expression tag |
| Ile 499 | - | expression tag |
| Glu 500 | - | expression tag |
| Gly 501 | - | expression tag |
| Arg 502 | - | expression tag |
| Thr 503 | - | expression tag |
| Ser 504 | - | expression tag |
| Glu 505 | - | expression tag |
| Asp 506 | - | expression tag |
| Ala 507 | - | expression tag |
| Trp 508 | - | expression tag |
| Ser 509 | - | expression tag |
| His 510 | - | expression tag |
| Pro 511 | - | expression tag |
| Gln 512 | - | expression tag |
| Phe 513 | - | expression tag |
| Glu 514 | - | expression tag |
| Lys 515 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 86556.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 271.3 | |
| All* | Total formula weight | 86827.6 |
