9GI9
Wildtype EGFR bound with (R)-3-((3-chloro-2-methoxyphenyl)amino)-2-(3-((tetrahydrofuran-2-yl)methoxy)pyridin-4-yl)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Epidermal growth factor receptor | polymer | 330 | 37579.5 | 1 | UniProt (P00533) Pfam (PF07714) | Homo sapiens (human) | Proto-oncogene c-ErbB-1,Receptor tyrosine-protein kinase erbB-1 |
| 2 | B (A) | 3-[(3-chloranyl-2-methoxy-phenyl)amino]-2-[3-[[(2~{R})-oxolan-2-yl]methoxy]pyridin-4-yl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one | non-polymer | 468.9 | 1 | Chemie (A1ILZ) |
Sequence modifications
A: 696 - 1022 (UniProt: P00533)
| PDB | External Database | Details |
|---|---|---|
| Gly 693 | - | expression tag |
| Ser 694 | - | expression tag |
| Met 695 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37579.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 468.9 | |
| All* | Total formula weight | 38048.4 |
