9GI6
Structure of SARS-CoV-2 Main Protease (Mpro) with mutation of N214A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Replicase polyprotein 1a | polymer | 306 | 33782.5 | 2 | UniProt (A0A6M4EPN9) Pfam (PF05409) | Severe acute respiratory syndrome coronavirus 2 | ORF1a polyprotein |
| 2 | AA, C, D, E, F... (B, A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 23 | Chemie (PEG) | |||
| 3 | Q (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | BA, R (B, A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | CA, DA (A, B) | water | water | 18.0 | 310 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 306 (UniProt: A0A6M4EPN9)
| PDB | External Database | Details |
|---|---|---|
| Ala 214 | Asn 3477 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 67565.0 | |
| Non-Polymers* | Number of molecules | 26 |
| Total formula weight | 2522.2 | |
| All* | Total formula weight | 70087.2 |
