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9GH2

Human KRas4A (GMPPNP) in complex with compound 36

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
GTPase KRaspolymer17219607.11UniProt (P01116)
Pfam (PF00071)
Homo sapiens (human)K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras
2B
(A)
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTERnon-polymer522.21Chemie (GNP)
3C
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
4D, E
(A)
COBALT (II) IONnon-polymer58.92Chemie (CO)
5F
(A)
(3Z)-18-(4-aminocyclohexyl)-21-[4-(4-amino-1-piperidyl)-1-piperidyl]-7-chloro-10-hydroxy-2,2-dioxo-2-lambda-6,5-dithia-3,12,18,22-tetrazatetracyclo[18.3.1.04,12.06,11]tetracosa-1(23),3,6,8,10,20(24),21-heptaen-19-onenon-polymer731.41Chemie (A1ILF)
6G
(A)
waterwater18.058Chemie (HOH)
Sequence modifications
A: 1 - 169 (UniProt: P01116)
PDBExternal DatabaseDetails
Gly -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
Ser 118Cys 118engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight19607.1
Non-Polymers*Number of molecules5
Total formula weight1395.7
All*Total formula weight21002.8
*Water molecules are not included.

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PDB entries from 2025-07-09

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