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9GGY

Human KRas4A (GDP) in complex with compound 29

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
GTPase KRaspolymer17219607.11UniProt (P01116)
Pfam (PF00071)
Homo sapiens (human)K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras
2B
(A)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
3C
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
4D, E
(A)
1,2-ETHANEDIOLnon-polymer62.12Chemie (EDO)
5F
(A)
12-(1-aza-5-azanidaspiro[4.5]decan-8-yl)-18-[(1-chloro-3-hydroxy-1,2,3-benzothiadiazol-5-yl)-lambda4-sulfanylidene]-4-hydroxy-3,3-dioxo-3lambda6-thia-1,4,12,17-tetraza-2lambda6-thia-6,10,19-triaza-3non-polymer713.31Chemie (A1IK3)
6G
(A)
waterwater18.0122Chemie (HOH)
Sequence modifications
A: 1 - 169 (UniProt: P01116)
PDBExternal DatabaseDetails
Gly -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
Ser 118Cys 118engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight19607.1
Non-Polymers*Number of molecules5
Total formula weight1305.0
All*Total formula weight20912.0
*Water molecules are not included.

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PDB entries from 2025-07-09

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