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9GGX

Human KRas4A (GMPPNP) in complex with compound 19

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
GTPase KRaspolymer17219607.11UniProt (P01116)
Pfam (PF00071)
Homo sapiens (human)K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras
2B
(A)
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTERnon-polymer522.21Chemie (GNP)
3C
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
4D
(A)
COBALT (II) IONnon-polymer58.91Chemie (CO)
5E
(A)
(3E,15S)-17-(cis-4-aminocyclohexyl)-7-chloro-10,15,20-trihydroxy-2,2-dioxo-2-lambda-6,5-dithia-3,12,17-triazatetracyclo[17.3.1.04,12.06,11]tricosa-1(22),3,6(11),7,9,19(23),20-heptaen-18-onenon-polymer567.11Chemie (A1IMB)
6F
(A)
waterwater18.0118Chemie (HOH)
Sequence modifications
A: 1 - 169 (UniProt: P01116)
PDBExternal DatabaseDetails
Gly -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
Ser 118Cys 118engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight19607.1
Non-Polymers*Number of molecules4
Total formula weight1172.5
All*Total formula weight20779.6
*Water molecules are not included.

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PDB entries from 2025-12-17

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