9GGM
Cryo-EM structure of KBTBD4 P313PRR mutant-HDAC2 2:2 complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C (A, C) | Isoform 1 of Kelch repeat and BTB domain-containing protein 4 | polymer | 520 | 58463.1 | 2 | UniProt (Q9NVX7) Pfam (PF00651) Pfam (PF07707) Pfam (PF07646) | Homo sapiens (human) | BTB and kelch domain-containing protein 4 |
2 | B, D (D, B) | Histone deacetylase 2 | polymer | 488 | 55443.2 | 2 | UniProt (Q92769) Pfam (PF00850) | Homo sapiens (human) | HD2,Protein deacylase HDAC2 |
3 | E, F (D, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence modifications
A, C: 17 - 536 (UniProt: Q9NVX7)
PDB | External Database | Details |
---|---|---|
Pro 311 | - | insertion |
Arg 312 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 227812.4 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 130.8 | |
All* | Total formula weight | 227943.2 |