9GGH
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 (CD2) in complex with N-((6-(Hydroxyamino)-6-oxohexyl)oxy)-4-(4-(pyrrolidin-1-yl)phenyl)thiazole-2-carboxamide
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histone deacetylase 6 | polymer | 364 | 40285.5 | 1 | UniProt (F8W4B7) Pfam (PF00850) | Danio rerio (zebrafish) | |
| 2 | B (A) | ~{N}-[6-(oxidanylamino)-6-oxidanylidene-hexoxy]-4-(4-pyrrolidin-1-ylphenyl)-1,3-thiazolidine-2-carboxamide | non-polymer | 418.5 | 1 | Chemie (A1IKY) | |||
| 3 | C, D, E, F, G (A) | ZINC ION | non-polymer | 65.4 | 5 | Chemie (ZN) | |||
| 4 | H (A) | water | water | 18.0 | 29 | Chemie (HOH) |
Sequence modifications
A: 440 - 798 (UniProt: F8W4B7)
| PDB | External Database | Details |
|---|---|---|
| Ser 435 | - | expression tag |
| Asn 436 | - | expression tag |
| Ala 437 | - | expression tag |
| Gly 438 | - | expression tag |
| Gly 439 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40285.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 745.6 | |
| All* | Total formula weight | 41031.0 |
