9GFM
CryoEM structure of the human INO80 core-nucleosome complex state N-7
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | INO80 complex subunit B | polymer | 50 | 5759.3 | 1 | UniProt (Q9C086) | Homo sapiens (human) | High mobility group AT-hook 1-like 4,IES2 homolog,hIes2,PAP-1-associated protein 1,PAPA-1,Zinc finger HIT domain-containing protein 4 |
| 2 | B (K) | Nucleosomal DNA strand 1 | polymer | 139 | 43140.5 | 1 | synthetic construct | ||
| 3 | C (L) | Nucleosomal DNA strand 2 | polymer | 139 | 42664.2 | 1 | synthetic construct | ||
| 4 | D (M) | Histone H3.1 | polymer | 93 | 10791.7 | 1 | UniProt (P68431) Pfam (PF00125) | Homo sapiens (human) | Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l |
| 5 | E (N) | Histone H4 | polymer | 82 | 9279.9 | 1 | UniProt (P62805) Pfam (PF15511) | Homo sapiens (human) | |
| 6 | F (O) | Histone H2A type 1-B/E | polymer | 106 | 11637.6 | 1 | UniProt (P04908) Pfam (PF00125) Pfam (PF16211) | Homo sapiens (human) | Histone H2A.2,Histone H2A/a,Histone H2A/m |
| 7 | G (P) | Histone H2B type 2-E | polymer | 96 | 10750.4 | 1 | UniProt (Q16778) Pfam (PF00125) | Homo sapiens (human) | H2B-clustered histone 21,Histone H2B-GL105,Histone H2B.q,H2B/q |
| 8 | H (Q) | Histone H3.1 | polymer | 100 | 11762.8 | 1 | UniProt (P68431) Pfam (PF00125) | Homo sapiens (human) | Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l |
| 9 | I (R) | Histone H4 | polymer | 79 | 8910.4 | 1 | UniProt (P62805) Pfam (PF15511) | Homo sapiens (human) | |
| 10 | J (S) | Histone H2A type 1-B/E | polymer | 111 | 12123.2 | 1 | UniProt (P04908) Pfam (PF00125) Pfam (PF16211) | Homo sapiens (human) | Histone H2A.2,Histone H2A/a,Histone H2A/m |
| 11 | K (T) | Histone H2B type 2-E | polymer | 93 | 10420.9 | 1 | UniProt (Q16778) Pfam (PF00125) | Homo sapiens (human) | H2B-clustered histone 21,Histone H2B-GL105,Histone H2B.q,H2B/q |
Sequence modifications
P: 30 - 125 (UniProt: Q16778)
| PDB | External Database | Details |
|---|---|---|
| Ala 124 | Ser 125 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 11 |
| Total formula weight | 177240.9 | |
| All* | Total formula weight | 177240.9 |
