9GFJ

Crystal structure of ASO binding Fab fragment with ASO143

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (H)	Fab fragment heavy chain	polymer	226	23559.3	1		Homo sapiens
2	B (L)	Fab fragment light chain	polymer	219	24070.9	1		Homo sapiens
3	C, D, E, F, G... (H, L)	1,2-ETHANEDIOL	non-polymer		62.1	8	Chemie (EDO)
4	I (L)	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID	non-polymer		238.3	1	Chemie (EPE)
5	L (L)	1-[(1~{S},3~{R},4~{R},7~{S})-7-[[(1~{R},3~{R},4~{R},7~{S})-7-[[(1~{R},3~{R},4~{R},7~{S})-3-(6-aminopurin-9-yl)-7-[[(1~{R},3~{R},4~{R},7~{S})-3-(4-azanyl-5-methyl-2-oxidanylidene-pyrimidin-1-yl)-7-oxidanyl-2,5-dioxabicyclo[2.2.1]heptan-1-yl]methoxy-sulfanyl-phosphoryl]oxy-2,5-dioxabicyclo[2.2.1]heptan-1-yl]methoxy-sulfanyl-phosphoryl]oxy-3-(4-azanyl-5-methyl-2-oxidanylidene-pyrimidin-1-yl)-2,5-dioxabicyclo[2.2.1]heptan-1-yl]methoxy-sulfanyl-phosphoryl]oxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-5-methyl-pyrimidine-2,4-dione	non-polymer		1322.1	1	Chemie (A1IKV)
6	M, N (H, L)	water	water		18.0	411	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	47630.2
Non-Polymers*	Number of molecules	10
	Total formula weight	2056.9
All*	Total formula weight	49687.1

*Water molecules are not included.