9GFB
CryoEM structure of the human INO80 core-nucleosome complex state N-7
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | RuvB-like 1 | polymer | 456 | 50296.9 | 3 | UniProt (Q9Y265) Pfam (PF06068) Pfam (PF17856) | Homo sapiens (human) | 49 kDa TATA box-binding protein-interacting protein,49 kDa TBP-interacting protein,54 kDa erythrocyte cytosolic protein,ECP-54,INO80 complex subunit H,Nuclear matrix protein 238,NMP 238,Pontin 52,TIP49a,TIP60-associated protein 54-alpha,TAP54-alpha |
| 2 | D, E, F (D, E, F) | RuvB-like 2 | polymer | 463 | 51222.5 | 3 | UniProt (Q9Y230) Pfam (PF06068) Pfam (PF17856) | Homo sapiens (human) | 48 kDa TATA box-binding protein-interacting protein,48 kDa TBP-interacting protein,51 kDa erythrocyte cytosolic protein,ECP-51,INO80 complex subunit J,Repressing pontin 52,Reptin 52,TIP49b,TIP60-associated protein 54-beta,TAP54-beta |
| 3 | G (G) | Chromatin-remodeling ATPase INO80 | polymer | 1556 | 177032.8 | 1 | UniProt (Q9ULG1) Pfam (PF13892) Pfam (PF00176) Pfam (PF00271) | Homo sapiens (human) | hINO80,DNA helicase-related INO80 complex homolog 1,DNA helicase-related protein INO80,INO80 complex subunit A |
| 4 | H (H) | INO80 complex subunit B | polymer | 356 | 38704.2 | 1 | UniProt (Q9C086) Pfam (PF04795) Pfam (PF04438) | Homo sapiens (human) | High mobility group AT-hook 1-like 4,IES2 homolog,hIes2,PAP-1-associated protein 1,PAPA-1,Zinc finger HIT domain-containing protein 4 |
| 5 | I (I) | INO80 complex subunit C | polymer | 192 | 20672.6 | 1 | UniProt (Q6PI98) Pfam (PF08265) | Homo sapiens (human) | IES6 homolog,hIes6 |
| 6 | J (J) | Actin-related protein 5 | polymer | 607 | 68372.3 | 1 | UniProt (Q9H9F9) Pfam (PF00022) | Homo sapiens (human) | hARP5,Sarcoma antigen NY-SAR-16 |
| 7 | K (K) | Nucleosomal DNA strand 1 | polymer | 152 | 47121.1 | 1 | synthetic construct | ||
| 8 | L (L) | Nucleosomal DNA strand 2 | polymer | 152 | 46715.8 | 1 | synthetic construct | ||
| 9 | M, Q (M, Q) | Histone H3.1 | polymer | 136 | 15437.2 | 2 | UniProt (P68431) Pfam (PF00125) | Homo sapiens (human) | Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l |
| 10 | N, R (N, R) | Histone H4 | polymer | 102 | 11263.2 | 2 | UniProt (P62805) Pfam (PF15511) | Homo sapiens (human) | |
| 11 | O, S (O, S) | Histone H2A type 1-B/E | polymer | 129 | 14034.4 | 2 | UniProt (P04908) Pfam (PF00125) Pfam (PF16211) | Homo sapiens (human) | Histone H2A.2,Histone H2A/a,Histone H2A/m |
| 12 | P, T (P, T) | Histone H2B type 2-E | polymer | 125 | 13820.0 | 2 | UniProt (Q16778) Pfam (PF00125) | Homo sapiens (human) | H2B-clustered histone 21,Histone H2B-GL105,Histone H2B.q,H2B/q |
| 13 | U (A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 14 | AA, V, W, X, Y... (G, B, C, D, E...) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 6 | Chemie (ADP) | |||
| 15 | BA (H) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 20 |
| Total formula weight | 812286.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 3135.8 | |
| All* | Total formula weight | 815422.2 |
