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9GE5

CryoEM structure of the human INO80-Hexasome complex

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
RuvB-like 1polymer45349905.33UniProt (Q9Y265)
Pfam (PF06068)
Pfam (PF17856)
Homo sapiens (human)49 kDa TATA box-binding protein-interacting protein,49 kDa TBP-interacting protein,54 kDa erythrocyte cytosolic protein,ECP-54,INO80 complex subunit H,Nuclear matrix protein 238,NMP 238,Pontin 52,TIP49a,TIP60-associated protein 54-alpha,TAP54-alpha
2D, E, F
(D, E, F)
RuvB-like 2polymer43948627.53UniProt (Q9Y230)
Pfam (PF06068)
Pfam (PF17856)
Homo sapiens (human)48 kDa TATA box-binding protein-interacting protein,48 kDa TBP-interacting protein,51 kDa erythrocyte cytosolic protein,ECP-51,INO80 complex subunit J,Repressing pontin 52,Reptin 52,TIP49b,TIP60-associated protein 54-beta,TAP54-beta
3G
(G)
Chromatin-remodeling ATPase INO80polymer73385303.41UniProt (Q9ULG1)
Pfam (PF00176)
Pfam (PF00271)
Homo sapiens (human)hINO80,DNA helicase-related INO80 complex homolog 1,DNA helicase-related protein INO80,INO80 complex subunit A
4H
(H)
INO80 complex subunit Bpolymer13514692.91UniProt (Q9C086)
Pfam (PF04795)
Pfam (PF04438)
Homo sapiens (human)High mobility group AT-hook 1-like 4,IES2 homolog,hIes2,PAP-1-associated protein 1,PAPA-1,Zinc finger HIT domain-containing protein 4
5I
(I)
INO80 complex subunit Cpolymer10712015.61UniProt (Q6PI98)
Pfam (PF08265)
Homo sapiens (human)IES6 homolog,hIes6
6J
(J)
Actin-related protein 5polymer57665589.41UniProt (Q9H9F9)
Pfam (PF00022)
Homo sapiens (human)hARP5,Sarcoma antigen NY-SAR-16
7K
(K)
Hexasomal DNA Strand 1polymer11335098.41synthetic construct
8L
(L)
Hexasomal DNA strand 2polymer11334640.11synthetic construct
9M, O
(M, Q)
Histone H3.1polymer9410948.82UniProt (P68431)
Pfam (PF00125)
Homo sapiens (human)Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l
10N, P
(N, R)
Histone H4polymer819180.72UniProt (P62805)
Pfam (PF15511)
Homo sapiens (human)
11Q
(S)
Histone H2A type 1-B/Epolymer10811865.91UniProt (P04908)
Pfam (PF00125)
Pfam (PF16211)
Homo sapiens (human)Histone H2A.2,Histone H2A/a,Histone H2A/m
12R
(T)
Histone H2B type 1-Bpolymer9210263.81UniProt (P33778)
Pfam (PF00125)
Homo sapiens (human)H2B-clustered histone 3,Histone H2B.1,Histone H2B.f,H2B/f
13S
(A)
ADENOSINE-5'-TRIPHOSPHATEnon-polymer507.21Chemie (ATP)
14AA, T, U, V, W...
(J, B, C, D, E...)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.27Chemie (ADP)
15Z
(H)
ZINC IONnon-polymer65.41Chemie (ZN)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains18
Total formula weight605327.1
Non-Polymers*Number of molecules9
Total formula weight3563.0
All*Total formula weight608890.1
*Water molecules are not included.

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PDB entries from 2025-08-27

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