9GE4
CryoEM structure of the human INO80 core- H2A.Z nucleosome complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (K) | Nucleosome DNA strand 1 (152-MER) | polymer | 152 | 47121.1 | 1 | synthetic construct | ||
| 2 | B (L) | Nucleosome DNA strand 2 (152-MER) | polymer | 152 | 46715.8 | 1 | synthetic construct | ||
| 3 | C, G (M, Q) | Histone H3.1 | polymer | 136 | 15437.2 | 2 | UniProt (P68431) Pfam (PF00125) | Homo sapiens (human) | Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l |
| 4 | D, H (N, R) | Histone H4 | polymer | 102 | 11263.2 | 2 | UniProt (P62805) Pfam (PF15511) | Homo sapiens (human) | |
| 5 | E (O) | Histone H2A.Z | polymer | 127 | 13450.6 | 1 | UniProt (P0C0S5) Pfam (PF00125) Pfam (PF16211) | Homo sapiens (human) | H2A/z |
| 6 | F, J (P, T) | Histone H2B type 2-E | polymer | 125 | 13820.0 | 2 | UniProt (Q16778) Pfam (PF00125) | Homo sapiens (human) | H2B-clustered histone 21,Histone H2B-GL105,Histone H2B.q,H2B/q |
| 7 | I (S) | Histone H2A.Z | polymer | 127 | 13450.6 | 1 | UniProt (P0C0S5) Pfam (PF00125) Pfam (PF16211) | Homo sapiens (human) | H2A/z |
Sequence modifications
S: -1 - 125 (UniProt: P0C0S5)
| PDB | External Database | Details |
|---|---|---|
| Leu 108 | Ile 111 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 201778.9 | |
| All* | Total formula weight | 201778.9 |
