9GD7
DNA-PK Ku80 mediated dimer bound to DNA polymerase Lambda and DNA ligase 4/XRCC4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (E) | DNA ligase 4 | polymer | 911 | 104125.0 | 1 | UniProt (P49917) Pfam (PF00533) Pfam (PF04675) Pfam (PF01068) Pfam (PF04679) Pfam (PF11411) | Homo sapiens (human) | DNA ligase IV,Polydeoxyribonucleotide synthase [ATP] 4 |
| 2 | B (L) | X-ray repair cross-complementing protein 5 | polymer | 732 | 82812.4 | 1 | UniProt (P13010) Pfam (PF03731) Pfam (PF02735) Pfam (PF03730) Pfam (PF08785) | Homo sapiens (human) | 86 kDa subunit of Ku antigen,ATP-dependent DNA helicase 2 subunit 2,ATP-dependent DNA helicase II 80 kDa subunit,CTC box-binding factor 85 kDa subunit,CTCBF,DNA repair protein XRCC5,Ku80,Ku86,Lupus Ku autoantigen protein p86,Nuclear factor IV,Thyroid-lupus autoantigen,TLAA,X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) |
| 3 | C (M) | Protein PAXX | polymer | 204 | 21663.5 | 1 | UniProt (Q9BUH6) Pfam (PF15384) | Homo sapiens (human) | Paralog of XRCC4 and XLF,XRCC4-like small protein |
| 4 | D, E (P, Q) | DNA repair protein XRCC4 | polymer | 336 | 38337.7 | 2 | UniProt (Q13426) Pfam (PF06632) Pfam (PF21924) Pfam (PF21925) | Homo sapiens (human) | X-ray repair cross-complementing protein 4 |
| 5 | F (S) | DNA-dependent protein kinase catalytic subunit | polymer | 4128 | 469673.2 | 1 | UniProt (P78527) Pfam (PF20502) Pfam (PF08163) Pfam (PF19704) Pfam (PF02259) Pfam (PF00454) Pfam (PF02260) | Homo sapiens (human) | DNA-PK catalytic subunit,DNA-PKcs,DNPK1,p460 |
| 6 | G (T) | X-ray repair cross-complementing protein 6 | polymer | 609 | 69945.0 | 1 | UniProt (P12956) Pfam (PF03731) Pfam (PF02735) Pfam (PF03730) Pfam (PF02037) | Homo sapiens (human) | 5'-deoxyribose-5-phosphate lyase Ku70,5'-dRP lyase Ku70,70 kDa subunit of Ku antigen,ATP-dependent DNA helicase 2 subunit 1,ATP-dependent DNA helicase II 70 kDa subunit,CTC box-binding factor 75 kDa subunit,CTCBF,DNA repair protein XRCC6,Lupus Ku autoantigen protein p70,Ku70,Thyroid-lupus autoantigen,TLAA,X-ray repair complementing defective repair in Chinese hamster cells 6 |
| 7 | H (i) | DNA | polymer | 25 | 7632.0 | 1 | Homo sapiens | ||
| 8 | I (j) | DNA | polymer | 25 | 7748.0 | 1 | Homo sapiens | ||
| 9 | J (A) | DNA polymerase lambda | polymer | 575 | 63571.2 | 1 | UniProt (Q9UGP5) Pfam (PF14716) Pfam (PF10391) Pfam (PF14792) Pfam (PF14791) | Homo sapiens (human) | Pol Lambda,DNA polymerase beta-2,Pol beta2,DNA polymerase kappa |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 903845.8 | |
| All* | Total formula weight | 903845.8 |
