9GCF
HUMAN PI3KDELTA IN COMPLEX WITH ISOCUMARIN INHIBITOR CHF-6523
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | polymer | 1044 | 119633.0 | 1 | UniProt (O00329) Pfam (PF02192) Pfam (PF00794) Pfam (PF00792) Pfam (PF00613) Pfam (PF00454) | Homo sapiens (human) | PI3-kinase subunit delta,PI3K-delta,PI3Kdelta,PtdIns-3-kinase subunit delta,Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta,PtdIns-3-kinase subunit p110-delta,p110delta |
| 2 | B (B) | Phosphatidylinositol 3-kinase regulatory subunit alpha | polymer | 170 | 20993.7 | 1 | UniProt (P23727) Pfam (PF16454) | Bos taurus (domestic cattle) | PI3-kinase regulatory subunit alpha,PI3K regulatory subunit alpha,PtdIns-3-kinase regulatory subunit alpha,Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha,PI3-kinase subunit p85-alpha,PtdIns-3-kinase regulatory subunit p85-alpha |
| 3 | C (A) | 3-[(1S)-1-[4-azanyl-3-(5-oxidanylpyridin-3-yl)pyrazolo[3,4-d]pyrimidin-1-yl]ethyl]-4-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]isochromen-1-one | non-polymer | 588.7 | 1 | Chemie (A1IJ5) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 140626.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 588.7 | |
| All* | Total formula weight | 141215.3 |
