9G9T
Cryo-EM structure of the Toxoplasma gondii respiratory chain complex III inhibited by ELQ-300
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, M (A, a) | Cytochrome b | polymer | 360 | 40794.4 | 2 | UniProt (O20672) Pfam (PF00033) Pfam (PF00032) | Toxoplasma gondii | Complex III subunit 3,Complex III subunit III,Cytochrome b-c1 complex subunit 3,Ubiquinol-cytochrome-c reductase complex cytochrome b subunit |
| 2 | B, N (B, b) | Cytochrome c1, heme protein | polymer | 398 | 46025.4 | 2 | UniProt (S7W9J5) Pfam (PF02167) | Toxoplasma gondii | |
| 3 | C, O (C, c) | Putative ubiquinol cytochrome c oxidoreductase | polymer | 487 | 54869.1 | 2 | UniProt (S7UK06) Pfam (PF00355) | Toxoplasma gondii | |
| 4 | D, P (D, d) | Putative peptidase M16 family protein | polymer | 509 | 56986.8 | 2 | UniProt (S7W617) Pfam (PF00675) Pfam (PF05193) | Toxoplasma gondii | |
| 5 | E, Q (E, e) | Alpha-MPP | polymer | 563 | 62238.4 | 2 | UniProt (A0A125YN38) Pfam (PF00675) Pfam (PF05193) | Toxoplasma gondii | |
| 6 | F, R (F, f) | Putative ubiquinol-cytochrome c reductase hinge protein | polymer | 89 | 10509.1 | 2 | UniProt (S7VSS5) Pfam (PF02320) | Toxoplasma gondii | |
| 7 | G, S (G, g) | Ubiquinol-cytochrome c reductase | polymer | 234 | 26777.6 | 2 | UniProt (A0A125YYJ3) Pfam (PF02271) | Toxoplasma gondii | |
| 8 | H, T (H, h) | QCR8/TGGT1_227910 | polymer | 122 | 14391.7 | 2 | UniProt (A0A125YW19) | Toxoplasma gondii | |
| 9 | I, U (I, i) | Ubiquinol-cytochrome C family reductase UQCRX/QCR9-like protein | polymer | 128 | 15290.6 | 2 | UniProt (S7UVH4) Pfam (PF05365) | Toxoplasma gondii | |
| 10 | J, V (J, j) | Transmembrane protein | polymer | 80 | 9455.9 | 2 | UniProt (S7UR33) | Toxoplasma gondii | |
| 11 | K, W (K, k) | Transmembrane protein | polymer | 141 | 15250.6 | 2 | UniProt (A0A125YZN9) | Toxoplasma gondii | |
| 12 | L, X (L, l) | Transmembrane protein | polymer | 109 | 11723.7 | 2 | UniProt (S7UTB5) | Toxoplasma gondii | |
| 13 | AB, BB, CB, GA, HA... (g, h, C, D, G...) | CARDIOLIPIN | non-polymer | 1464.0 | 16 | Chemie (CDL) | |||
| 14 | AA, QA, RA, Z (A, a) | 6-chloranyl-7-methoxy-2-methyl-3-[4-[4-(trifluoromethyloxy)phenoxy]phenyl]-1~{H}-quinolin-4-one | non-polymer | 475.8 | 4 | Chemie (A1IJD) | |||
| 15 | BA, CA, SA, TA (A, a) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 4 | Chemie (HEM) | |||
| 16 | DA, UA (A, a) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 17 | EA, VA (B, b) | HEME C | non-polymer | 618.5 | 2 | Chemie (HEC) | |||
| 18 | DB, FA (i, C) | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 790.1 | 2 | Chemie (PC1) | |||
| 19 | JA, ZA (D, d) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 20 | AC, BC, EB, FB, GB... (k, l, A, B, C...) | water | water | 18.0 | 683 | Chemie (HOH) |
Sequence modifications
A, a: 10 - 368 (UniProt: O20672)
| PDB | External Database | Details |
|---|---|---|
| Phe 9 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 24 |
| Total formula weight | 728626.5 | |
| Non-Polymers* | Number of molecules | 32 |
| Total formula weight | 30790.7 | |
| All* | Total formula weight | 759417.2 |
