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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

9G8O

human 40S ribosome bound by a SKI238-exosome complex

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(B)		Superkiller complex protein 3polymer1568176064.81UniProt (Q6PGP7)
Pfam (PF13181)
Pfam (PF14559)
Pfam (PF13432)		Homo sapiens (human)Ski3,Tetratricopeptide repeat protein 37,TPR repeat protein 37,Tricho-hepatic-enteric syndrome protein,Thespin
2B, C
(C, D)		WD repeat-containing protein 61polymer30533617.52UniProt (Q9GZS3)
Pfam (PF00400)		Homo sapiens (human)Meiotic recombination REC14 protein homolog,SKI8 homolog,Ski8
3D
(F)		Exosome complex component RRP42polymer29532216.81UniProt (Q15024)
Pfam (PF01138)
Pfam (PF03725)		Homo sapiens (human)Exosome component 7,Ribosomal RNA-processing protein 42,p8
4E
(J)		Exosome complex component CSL4polymer19921835.11UniProt (Q9Y3B2)
Pfam (PF14382)
Pfam (PF10447)		Homo sapiens (human)Exosome component 1
5F
(K)		Exosome complex component RRP45polymer44349370.31UniProt (Q06265)
Pfam (PF01138)
Pfam (PF03725)		Homo sapiens (human)Autoantigen PM/Scl 1,Exosome component 9,P75 polymyositis-scleroderma overlap syndrome-associated autoantigen,Polymyositis/scleroderma autoantigen 1,Polymyositis/scleroderma autoantigen 75 kDa,PM/Scl-75
6G
(L)		Exosome complex component RRP43polymer28030429.91UniProt (Q96B26)
Pfam (PF01138)
Pfam (PF03725)		Homo sapiens (human)Exosome component 8,Opa-interacting protein 2,OIP-2,Ribosomal RNA-processing protein 43,p9
7H
(N)		Exosome complex component RRP41polymer24526417.01UniProt (Q9NPD3)
Pfam (PF01138)
Pfam (PF03725)		Homo sapiens (human)Exosome component 4,Ribosomal RNA-processing protein 41,p12A
8I
(O)		Exosome complex component RRP46polymer23925636.31UniProt (Q9NQT4)
Pfam (PF01138)
Pfam (PF03725)		Homo sapiens (human)Chronic myelogenous leukemia tumor antigen 28,Exosome component 5,Ribosomal RNA-processing protein 46,p12B
9J
(A)		Helicase SKI2Wpolymer1246137913.71UniProt (Q15477)
Pfam (PF17911)
Pfam (PF00270)
Pfam (PF00271)
Pfam (PF21408)
Pfam (PF13234)
Pfam (PF08148)		Homo sapiens (human)Ski2,Helicase-like protein,HLP
10K
(E)		Isoform 2 of HBS1-like proteinpolymer27430196.11UniProt (Q9Y450)Homo sapiens (human)ERFS
11L
(G)		Exosome complex component MTR3polymer27228267.11UniProt (Q5RKV6)
Pfam (PF01138)		Homo sapiens (human)Exosome component 6,mRNA transport regulator 3 homolog,hMtr3,p11
12M
(H)		Exosome complex component RRP40polymer27929940.51UniProt (Q9NQT5)
Pfam (PF21261)
Pfam (PF21262)
Pfam (PF15985)		Homo sapiens (human)Exosome component 3,Ribosomal RNA-processing protein 40,p10
13N
(I)		Exosome complex component RRP4polymer29733190.41UniProt (Q13868)
Pfam (PF14382)
Pfam (PF21266)
Pfam (PF15985)		Homo sapiens (human)Exosome component 2,Ribosomal RNA-processing protein 4
14O
(X)		CrPV-IRES RNApolymer25079334.01Cricket paralysis virus
15P
(Ln)		60S ribosomal protein L41polymer253473.51UniProt (P62945)
Pfam (PF05162)		Homo sapiens (human)HG12,Large ribosomal subunit protein eL41
16Q
(M)		DIS3-like exonuclease 1polymer1096125230.01UniProt (Q8TF46)
Pfam (PF17216)
Pfam (PF17849)
Pfam (PF00773)
Pfam (PF17215)		Homo sapiens (human)
17R
(S2)		18S ribosomal RNApolymer1869602752.91Homo sapiens
18S
(SA)		40S ribosomal protein SApolymer29532883.91UniProt (P08865)
Pfam (PF00318)
Pfam (PF16122)		Homo sapiens (human)37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Colon carcinoma laminin-binding protein,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40,Multidrug resistance-associated protein MGr1-Ag,NEM/1CHD4,Small ribosomal subunit protein uS2
19T
(SB)		40S ribosomal protein S3apolymer26430002.11UniProt (P61247)
Pfam (PF01015)		Homo sapiens (human)Small ribosomal subunit protein eS1,v-fos transformation effector protein,Fte-1
20U
(SC)		40S ribosomal protein S2polymer29331376.51UniProt (P15880)
Pfam (PF00333)
Pfam (PF03719)		Homo sapiens (human)40S ribosomal protein S4,Protein LLRep3,Small ribosomal subunit protein uS5
21V
(SD)		40S ribosomal protein S3polymer24326729.41UniProt (P23396)
Pfam (PF07650)
Pfam (PF00189)		Homo sapiens (human)Small ribosomal subunit protein uS3
22W
(SE)		40S ribosomal protein S4, X isoformpolymer26329654.91UniProt (P62701)
Pfam (PF08071)
Pfam (PF00900)
Pfam (PF00467)
Pfam (PF16121)		Homo sapiens (human)SCR10,Single copy abundant mRNA protein,Small ribosomal subunit protein eS4
23X
(SF)		40S ribosomal protein S5polymer20422913.51UniProt (P46782)
Pfam (PF00177)		Homo sapiens (human)Small ribosomal subunit protein uS7
24Y
(SG)		40S ribosomal protein S6polymer24928751.91UniProt (P62753)
Pfam (PF01092)		Homo sapiens (human)Phosphoprotein NP33,Small ribosomal subunit protein eS6
25Z
(SH)		40S ribosomal protein S7polymer19422168.91UniProt (P62081)
Pfam (PF01251)		Homo sapiens (human)Small ribosomal subunit protein eS7
26AA
(SI)		40S ribosomal protein S8polymer20824263.41UniProt (P62241)
Pfam (PF01201)		Homo sapiens (human)Small ribosomal subunit protein eS8
27BA
(SJ)		40S ribosomal protein S9polymer19422641.61UniProt (P46781)
Pfam (PF00163)
Pfam (PF01479)		Homo sapiens (human)Small ribosomal subunit protein uS4
28CA
(SK)		40S ribosomal protein S10polymer16518933.81UniProt (P46783)
Pfam (PF03501)		Homo sapiens (human)Small ribosomal subunit protein eS10
29DA
(SL)		40S ribosomal protein S11polymer15818468.81UniProt (P62280)
Pfam (PF16205)
Pfam (PF00366)		Homo sapiens (human)Small ribosomal subunit protein uS17
30EA
(SM)		40S ribosomal protein S12polymer13214548.91UniProt (P25398)
Pfam (PF01248)		Homo sapiens (human)Small ribosomal subunit protein eS12
31FA
(SN)		40S ribosomal protein S13polymer15117259.41UniProt (P62277)
Pfam (PF08069)
Pfam (PF00312)		Homo sapiens (human)Small ribosomal subunit protein uS15
32GA
(SO)		40S ribosomal protein S14polymer15116302.81UniProt (P62263)
Pfam (PF00411)		Homo sapiens (human)Small ribosomal subunit protein uS11
33HA
(SP)		40S ribosomal protein S15polymer14517076.21UniProt (P62841)
Pfam (PF00203)		Homo sapiens (human)RIG protein,Small ribosomal subunit protein uS19
34IA
(SQ)		40S ribosomal protein S16polymer14616477.41UniProt (P62249)
Pfam (PF00380)		Homo sapiens (human)Small ribosomal subunit protein uS9
35JA
(SR)		40S ribosomal protein S17polymer13515578.21UniProt (P08708)
Pfam (PF00833)		Homo sapiens (human)Small ribosomal subunit protein eS17
36KA
(SS)		40S ribosomal protein S18polymer15217759.81UniProt (P62269)
Pfam (PF00416)		Homo sapiens (human)Ke-3,Ke3,Small ribosomal subunit protein uS13
37LA
(ST)		40S ribosomal protein S19polymer14516091.61UniProt (P39019)
Pfam (PF01090)		Homo sapiens (human)Small ribosomal subunit protein eS19
38MA
(SU)		40S ribosomal protein S20polymer11913398.81UniProt (P60866)
Pfam (PF00338)		Homo sapiens (human)Small ribosomal subunit protein uS10
39NA
(SV)		40S ribosomal protein S21polymer839124.41UniProt (P63220)
Pfam (PF01249)		Homo sapiens (human)Small ribosomal subunit protein eS21
40OA
(SW)		40S ribosomal protein S15apolymer13014865.61UniProt (P62244)
Pfam (PF00410)		Homo sapiens (human)Small ribosomal subunit protein uS8
41PA
(SX)		40S ribosomal protein S23polymer14315844.71UniProt (P62266)
Pfam (PF00164)		Homo sapiens (human)Small ribosomal subunit protein uS12
42QA
(SY)		40S ribosomal protein S24polymer13315463.31UniProt (P62847)
Pfam (PF01282)		Homo sapiens (human)Small ribosomal subunit protein eS24
43RA
(SZ)		40S ribosomal protein S25polymer12513776.21UniProt (P62851)
Pfam (PF03297)		Homo sapiens (human)Small ribosomal subunit protein eS25
44SA
(Sa)		40S ribosomal protein S26polymer11513047.51UniProt (P62854)
Pfam (PF01283)		Homo sapiens (human)Small ribosomal subunit protein eS26
45TA
(Sb)		40S ribosomal protein S27polymer849480.21UniProt (P42677)
Pfam (PF01667)		Homo sapiens (human)Metallopan-stimulin 1,MPS-1,Small ribosomal subunit protein eS27
46UA
(Sc)		40S ribosomal protein S28polymer697855.11UniProt (P62857)
Pfam (PF01200)		Homo sapiens (human)Small ribosomal subunit protein eS28
47VA
(Sd)		40S ribosomal protein S29polymer566690.81UniProt (P62273)
Pfam (PF00253)		Homo sapiens (human)Small ribosomal subunit protein uS14
48WA
(Se)		40S ribosomal protein S30polymer596668.91UniProt (P62861)
Pfam (PF04758)		Homo sapiens (human)Small ribosomal subunit protein eS30
49XA
(Sf)		Ubiquitinpolymer15618004.01UniProt (P62979)
Pfam (PF00240)
Pfam (PF01599)		Homo sapiens (human)
50YA
(Sg)		Receptor of activated protein C kinase 1polymer31735115.71UniProt (P63244)
Pfam (PF00400)		Homo sapiens (human)Cell proliferation-inducing gene 21 protein,Guanine nucleotide-binding protein subunit beta-2-like 1,Guanine nucleotide-binding protein subunit beta-like protein 12.3,Human lung cancer oncogene 7 protein,HLC-7,Receptor for activated C kinase,Small ribosomal subunit protein RACK1
Sequence modifications
B: 1 - 1564 (UniProt: Q6PGP7)
PDBExternal DatabaseDetails
Gly -3-expression tag
Pro -2-expression tag
Asp -1-expression tag
Ser 0-expression tag
F: 1 - 291 (UniProt: Q15024)
PDBExternal DatabaseDetails
Gly -3-expression tag
Pro -2-expression tag
Asp -1-expression tag
Ser 0-expression tag
J: 1 - 195 (UniProt: Q9Y3B2)
PDBExternal DatabaseDetails
Gly -3-expression tag
Pro -2-expression tag
Asp -1-expression tag
Ser 0-expression tag
K: 1 - 439 (UniProt: Q06265)
PDBExternal DatabaseDetails
Gly -3-expression tag
Pro -2-expression tag
Asp -1-expression tag
Ser 0-expression tag
L: 1 - 276 (UniProt: Q96B26)
PDBExternal DatabaseDetails
Gly -3-expression tag
Pro -2-expression tag
Asp -1-expression tag
Ser 0-expression tag
O: 1 - 235 (UniProt: Q9NQT4)
PDBExternal DatabaseDetails
Gly -3-expression tag
Pro -2-expression tag
Asp -1-expression tag
Ser 0-expression tag
E: 369 - 632 (UniProt: Q9Y450)
PDBExternal DatabaseDetails
Gly 365-expression tag
Pro 366-expression tag
Asp 367-expression tag
Ser 368-expression tag
Leu 633-expression tag
Glu 634-expression tag
Val 635-expression tag
Leu 636-expression tag
Phe 637-expression tag
Gln 638-expression tag
H: 1 - 275 (UniProt: Q9NQT5)
PDBExternal DatabaseDetails
Gly -3-expression tag
Pro -2-expression tag
Asp -1-expression tag
Ser 0-expression tag
His 225Tyr 225variant
I: 1 - 293 (UniProt: Q13868)
PDBExternal DatabaseDetails
Gly -3-expression tag
Pro -2-expression tag
Asp -1-expression tag
Ser 0-expression tag
M: 1 - 1054 (UniProt: Q8TF46)
PDBExternal DatabaseDetails
Met -41-initiating methionine
Ser -40-expression tag
Ala -39-expression tag
Trp -38-expression tag
Ser -37-expression tag
His -36-expression tag
Pro -35-expression tag
Gln -34-expression tag
Phe -33-expression tag
Glu -32-expression tag
Lys -31-expression tag
Gly -30-expression tag
Gly -29-expression tag
Gly -28-expression tag
Ser -27-expression tag
Gly -26-expression tag
Gly -25-expression tag
Gly -24-expression tag
Ser -23-expression tag
Gly -22-expression tag
Gly -21-expression tag
Ser -20-expression tag
Ala -19-expression tag
Trp -18-expression tag
Ser -17-expression tag
His -16-expression tag
Pro -15-expression tag
Gln -14-expression tag
Phe -13-expression tag
Glu -12-expression tag
Lys -11-expression tag
Thr -10-expression tag
Ala -9-expression tag
Gly -8-expression tag
Leu -7-expression tag
Glu -6-expression tag
Val -5-expression tag
Leu -4-expression tag
Phe -3-expression tag
Gln -2-expression tag
Gly -1-expression tag
Pro 0-expression tag
Asn 486Asp 486conflict
SM: 1 - 132 (UniProt: P25398)
PDBExternal DatabaseDetails
Gln 52Leu 52conflict
Leu 69Cys 69conflict
Asn 99Lys 99conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains51
Total formula weight2118721.1
All*Total formula weight2118721.1
*Water molecules are not included.

238895

PDB entries from 2025-07-16

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