9G8N
80S-bound human Ski2-exosome complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | Exosome complex component RRP41 | polymer | 245 | 26417.0 | 1 | UniProt (Q9NPD3) Pfam (PF01138) Pfam (PF03725) | Homo sapiens (human) | Exosome component 4,Ribosomal RNA-processing protein 41,p12A |
| 2 | B (N) | Exosome complex component RRP43 | polymer | 280 | 30429.9 | 1 | UniProt (Q96B26) Pfam (PF01138) Pfam (PF03725) | Homo sapiens (human) | Exosome component 8,Opa-interacting protein 2,OIP-2,Ribosomal RNA-processing protein 43,p9 |
| 3 | C (O) | Exosome complex component RRP46 | polymer | 239 | 25636.3 | 1 | UniProt (Q9NQT4) Pfam (PF01138) Pfam (PF03725) | Homo sapiens (human) | Chronic myelogenous leukemia tumor antigen 28,Exosome component 5,Ribosomal RNA-processing protein 46,p12B |
| 4 | D (F) | Exosome complex component RRP42 | polymer | 295 | 32216.8 | 1 | UniProt (Q15024) Pfam (PF01138) Pfam (PF03725) | Homo sapiens (human) | Exosome component 7,Ribosomal RNA-processing protein 42,p8 |
| 5 | E (H) | Exosome complex component RRP40 | polymer | 279 | 29940.5 | 1 | UniProt (Q9NQT5) Pfam (PF21261) Pfam (PF21262) Pfam (PF15985) | Homo sapiens (human) | Exosome component 3,Ribosomal RNA-processing protein 40,p10 |
| 6 | F (J) | Exosome complex component CSL4 | polymer | 199 | 21835.1 | 1 | UniProt (Q9Y3B2) Pfam (PF14382) Pfam (PF10447) | Homo sapiens (human) | Exosome component 1 |
| 7 | G (X) | CrPV-IRES RNA | polymer | 44 | 13422.4 | 1 | Cricket paralysis virus | ||
| 8 | H (A) | Helicase SKI2W | polymer | 1246 | 137913.7 | 1 | UniProt (Q15477) Pfam (PF17911) Pfam (PF00270) Pfam (PF00271) Pfam (PF21408) Pfam (PF13234) Pfam (PF08148) | Homo sapiens (human) | Ski2,Helicase-like protein,HLP |
| 9 | I (G) | Exosome complex component MTR3 | polymer | 272 | 28267.1 | 1 | UniProt (Q5RKV6) Pfam (PF01138) | Homo sapiens (human) | Exosome component 6,mRNA transport regulator 3 homolog,hMtr3,p11 |
| 10 | J (I) | Exosome complex component RRP4 | polymer | 297 | 33190.4 | 1 | UniProt (Q13868) Pfam (PF14382) Pfam (PF21266) Pfam (PF15985) | Homo sapiens (human) | Exosome component 2,Ribosomal RNA-processing protein 4 |
| 11 | K (E) | Isoform 2 of HBS1-like protein | polymer | 274 | 30196.1 | 1 | UniProt (Q9Y450) | Homo sapiens (human) | ERFS |
| 12 | L (K) | Exosome complex component RRP45 | polymer | 443 | 49370.3 | 1 | UniProt (Q06265) Pfam (PF01138) Pfam (PF03725) | Homo sapiens (human) | Autoantigen PM/Scl 1,Exosome component 9,P75 polymyositis-scleroderma overlap syndrome-associated autoantigen,Polymyositis/scleroderma autoantigen 1,Polymyositis/scleroderma autoantigen 75 kDa,PM/Scl-75 |
| 13 | M (M) | DIS3-like exonuclease 1 | polymer | 1056 | 121108.6 | 1 | UniProt (Q8TF46) Pfam (PF17216) Pfam (PF17849) Pfam (PF00773) Pfam (PF17215) | Homo sapiens (human) |
Sequence modifications
N: 1 - 276 (UniProt: Q96B26)
O: 1 - 235 (UniProt: Q9NQT4)
F: 1 - 291 (UniProt: Q15024)
H: 1 - 275 (UniProt: Q9NQT5)
J: 1 - 195 (UniProt: Q9Y3B2)
I: 1 - 293 (UniProt: Q13868)
E: 369 - 632 (UniProt: Q9Y450)
K: 1 - 439 (UniProt: Q06265)
M: 1 - 1054 (UniProt: Q8TF46)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Ser 0 | - | expression tag |
| His 225 | Tyr 225 | variant |
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 365 | - | expression tag |
| Pro 366 | - | expression tag |
| Asp 367 | - | expression tag |
| Ser 368 | - | expression tag |
| Leu 633 | - | expression tag |
| Glu 634 | - | expression tag |
| Val 635 | - | expression tag |
| Leu 636 | - | expression tag |
| Phe 637 | - | expression tag |
| Gln 638 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
| Asn 486 | Asp 486 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 13 |
| Total formula weight | 579944.1 | |
| All* | Total formula weight | 579944.1 |
